Sirtris Exec Says Acquisition by GlaxoSmithKline is “Great for Boston”

After financial markets closed today, news broke that pharmaceutical giant GlaxoSmithKline (NYSE: [[ticker:GSK]]) will pay $720 million to acquire Cambridge, MA-based Sirtris Pharmaceuticals (NASDAQ: [[ticker:SIRT]]), which is researching and testing drugs for ageing-related conditions such as diabetes and cancer. A few minutes ago I spoke with Michelle Dipp, Sirtris’s corporate development director, about the acquisition. Here’s how the call went:

Xconomy: Congratulations. This is big news for Sirtris.

Michelle Dipp: Thanks. We’re really excited. This is an important step for our company, and we think that it’s great news for the company, the employees, the shareholders, and even for Boston.

X: Well, let’s talk about that. Often, when a far-away pharmaceutical giant buys a local biotech firm, there’s a general sense of disappointment—a feeling that this was a homegrown enterprise and now control is slipping away.

MD: I actually think it’s very different in this case. The reason is that Sirtris will operate as an autonomous unit of GlaxoSmithKline’s drug discovery organization. While it will become part of GSK, we will continue to operate here in our facilities in Cambridge, and in fact we will expand. We will not fully integrate into GSK. We will be owned by GSK, but we will expand and will operate independently.

X: Just last year Sirtris went public, and now you’re being acquired. In effect, you pursued one of the exits available to a startup, and now you’re taking the other. What opportunities does an acquisition present that going public didn’t?

MD: When you continue to access capital through the public market, you are forced to dilute yourself. This [offer] is a great deal for shareholders. It represents a really high multiple. Less than a year ago, we went public at $10 a share. This offer is for $22.50 a share, which is a really fantastic premium for our shareholders.

X: Right—it comes to $720 million. Does the company consider that a fair offer?

MD: Absolutely, yes, we think it’s a fair offer. But we don’t decide that as a company—that’s a board decision, with advice from a legal team and a banking team. We have had a unanimous decision by the board of Sirtris.

X: When do you expect to see the first effects of the acquisition, such as possible expansion?

MD: The details haven’t been ironed out yet. But we anticipate that we would operate as we had expected to at least through the end of the year.

X: Will there be synergies between Sirtris’s research, which is focused on sirtuin activation treating ageing-related diseases, and GSK’s own drug discovery programs?

MD: That’s a great question. There will certainly be synergies to the extent that we will have access to GSK’s research and development, and they are obviously a much larger and more sophisticated pharmaceutical company. What we can offer them is our entrepreneurial culture. This is a very fast-paced atmosphere, and we are hoping to infect the GSK culture with the Sirtris culture.

X: Does GSK have any other local facilities around Boston that you’ll be working with?

MD: They do have labs in the Boston area, but we’ll be liaising mainly with their Philadelphia headquarters.

Author: Wade Roush

Between 2007 and 2014, I was a staff editor for Xconomy in Boston and San Francisco. Since 2008 I've been writing a weekly opinion/review column called VOX: The Voice of Xperience. (From 2008 to 2013 the column was known as World Wide Wade.) I've been writing about science and technology professionally since 1994. Before joining Xconomy in 2007, I was a staff member at MIT’s Technology Review from 2001 to 2006, serving as senior editor, San Francisco bureau chief, and executive editor of TechnologyReview.com. Before that, I was the Boston bureau reporter for Science, managing editor of supercomputing publications at NASA Ames Research Center, and Web editor at e-book pioneer NuvoMedia. I have a B.A. in the history of science from Harvard College and a PhD in the history and social study of science and technology from MIT. I've published articles in Science, Technology Review, IEEE Spectrum, Encyclopaedia Brittanica, Technology and Culture, Alaska Airlines Magazine, and World Business, and I've been a guest of NPR, CNN, CNBC, NECN, WGBH and the PBS NewsHour. I'm a frequent conference participant and enjoy opportunities to moderate panel discussions and on-stage chats. My personal site: waderoush.com My social media coordinates: Twitter: @wroush Facebook: facebook.com/wade.roush LinkedIn: linkedin.com/in/waderoush Google+ : google.com/+WadeRoush YouTube: youtube.com/wroush1967 Flickr: flickr.com/photos/wroush/ Pinterest: pinterest.com/waderoush/