Seattle Non-Profit PATH Set to Launch “Ultra Rice” to Fight Global Malnutrition

to run the vitamin fortification process. It makes highly concentrated rice with one or more of the vitamins, which are shipped to a rice miller, and mixed in at a ratio of about 1 fortified rice grain for every 100 regular rice grains. That’s enough concentration to get the essential nutrients into the diet, without significantly changing the texture or appearance of a bowl of rice. (Grains with added iron can get discolored, but PATH has found people don’t mind eating them as long as the rest of the bowl contains white rice.)

The extra cost to produce the Ultra Rice is minimal, PATH’s Matthias says. At least one rice miller has shown interest in marketing it at the same price as regular rice, partly because they think they can mix in cheaper broken grains that otherwise might go to waste.

PATH considers the technique one of the most practical for fighting global malnutrition, Matthias says. Supplements are more costly, and people forget to take them, or don’t want to. Genetic modification of foods is another option, although that has stirred controversy overseas. “This way, kids get it at school. There are no compliance issues. We get better results,” Matthias says.

PATH has had some difficulties getting Ultra Rice to the masses, however. It struck a distribution deal in Brazil with a rice miller, through a contract that gave the miller control over the relationship with the pasta manufacturer. When the pasta manufacturer went bankrupt, the project stalled. A similar scenario happened in Colombia, Matthias says.

To prevent that from happening again, PATH tried a different strategy in China, licensing the Ultra Rice technology directly to a pasta-making company there that is part state-owned. In India, it also has deals directly with two pasta makers, Matthias says.

The project got a big boost earlier this year when a study by the Instituto de Salud Publica and PATH showed that the fortified rice isn’t just an intriguing idea, it can actually improve public health. The study found that women from six factories in the Mexican state of Morales had an 80 percent lower prevalence of anemia, and a 29 percent lower prevalence of iron deficiency if they ate iron-fortified rice, compared with those who ate the regular stuff.

Cox, for his part, says he’s happy with what PATH has done with the technology. His company donated the Vitamin-A fortification and micronutrient patent outright, and doesn’t stand to receive any royalties on product sales. He did retain the Ultra Rice trademark in case commercial uses emerge in the Western world, he said. The company is doing fine anyway, thanks to licenses it has sold for a bunch of inventions, including naturally pasteurized eggs, low-cholesterol eggs, and pollution control technology it licensed to Monsanto, Cox says.

“We’d like to get the vitamins to the kids who need them most. After we came up with the technology, it’s just not been as easy as we hoped to implement,” Cox says. “I think PATH is committed. As I get more experienced in business, I can see it takes human resources, capital resources, and technical resources aligned to accomplish a task of this magnitude. You need all of the pieces in place.”

Author: Luke Timmerman

Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.