ZymoGenetics, Bayer Drug Vying for European Regulatory Approval

ZymoGenetics is going to try to crack the European pharmaceutical market. The Seattle biotech company (NASDAQ: [[ticker:ZGEN]]) said today that its partner, Bayer, has filed an application with the European Union to market Recothrom, a drug for excess surgical bleeding.

The filing means ZymoGenetics will collect a $5 million milestone payment from Bayer (NYSE: [[ticker:BAY]]). Bayer will be responsible for commercializing the product in Europe, and will pay ZymoGenetics milestone payments and royalties on product sales there.

The drug was cleared for sale in the U.S. in January, but has gotten off to a slow start in this country as hospital purchasing committees have taken a long time to meet and decide on surgical bleeding drugs.

One difference in Europe: Recothrom won’t have to directly face off with King Pharmaceuticals’ Thrombin-JMI, a long-established competitor in the U.S. that’s derived from cow blood. Doctors in Europe use pressure, or expensive fibrin sealants to stop bleeding, said ZymoGenetics spokeswoman Susan Specht, in an email.

Whatever happens with the application in Europe, investors’ eyes are going to be fixated on Recothrom’s quarterly sales numbers in the U.S. If the company doesn’t start grabbing market share from the cow-blood derived product soon, shareholders are going to be even less happy than they are now.

Author: Luke Timmerman

Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.