Seattle Genetics Drug Fights Hodgkin’s, Frazier Sounds Off on Biotech Ventures, SBRI Pushes Malaria Vaccine, & More Seattle-Area Life Sciences News

much of the money into immunotherapy research in which scientists try to “teach” the immune system to fight cancer cells like a virus.

Calistoga Pharmceuticals, a Seattle-based biotech startup, got a small feather in its cap with an oral presentation at the American Society of Hematology, showing that it can kill cancer cells in the lab dish with a drug that blocks PI3 kinase. This is a hot target several companies are pursuing, as I described in a company profile back in October.

A new biotech company surfaced in town this week, Seattle-based Kineta. This outfit was formed by Shawn Iadonato and Charles Magness, after their previous company, Illumigen Biosciences, was acquired by Lexington, MA-based Cubist Pharmaceuticals. Kineta aims to trigger innate immunity against hepatitis C and other viral and immune diseases.

Zevalin, the slow-selling drug for non-Hodgkin’s lymphoma marketed by Seattle-based Cell Therapeutics, continued to show really promising results at a medical meeting. When patients were put in complete remission, they were kept there for at least 67 months on the drug, compared with 31 months for patients in a control group. The question is whether Cell Therapeutics has enough cash to survive as a company to capitalize on this.

—Kirkland, WA-based OVP Venture Partners named Carl Weissman to the elevated post of managing director. He’s still keeping his job as CEO of Seattle-based Accelerator, the startup incubator, although this means David Schubert is taking on some added responsibility with a promotion from chief business officer to president. Schubert played a key role in securing a new investment in Accelerator last month from PPD.

—Seattle-based PATH, the nonprofit devoted to improving global health, invested $3 million in a vaccine candidate against the deadly strain of H5N1 “bird” flu. The vaccine is in development by Lentigen, a Gaithersburg, MD-based biotech company.

Author: Luke Timmerman

Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.