San Diego Biotechs With Good News Step Forward at Roth Conference

filing its new drug application by June. The gel was developed to prevent infections in hospitalized patients who get catheters inserted into veins. About 325,000 catheter-related infections are reported worldwide each year—and some 40,000 to 80,000 people die from them annually, Cadence says.

—Cypress Bioscience (NASDAQ: [[ticker:CYPB]]) which got FDA approval in January for use of its drug milnacipran (brand name Savella) for patients with fibromyalgia, plans to begin marketing the drug in coming weeks. Sabrina Johnson, the biotech’s chief operating officer, says the company had about $150 million in available cash at the end of 2008, and corporate partner Forest Laboratories made a $25 million milestone payment to Cypress after the drug won FDA approval. That’s a nice war chest for Cypress as it sets out to jointly market the new drug with Forest. Johnson says Cypress already has hired 100 sales representatives who will focus their efforts on rheumatologists and pain specialists.

—NuVasive (NASDAQ: [[ticker:NUVA]]), CFO Kevin O’Boyle says the medical device company still expects sales growth of 40 percent in 2009, despite economic conditions. The company specializes in equipment and related products used in a pioneering surgical technique used to repair degenerated discs and other disorders of the spine. O’Boyle says the company provides training in its “lateral access technology” at its San Diego headquarters for between 400 and 500 orthopedic surgeons a year.

—Senomyx (NASDAQ: [[ticker: SNMX]]) CEO Kent Snyder says Swiss food giant Nestle is expected to launch new products in the United States this year that feature “savory” food enhancers the San Diego biotech has developed. The company screens hundreds of thousands of synthetic and natural molecules to identify compounds that interact with the four taste receptors on the tongue, savory, sweet, salty, and bitter. Four compounds that Senomyx has developed to enhance the savory taste, and as a replacement for MSG, have been approved for use in the United States. Snyder said another compound developed to enhance sucralose (better known as the artificial sweetener Splenda) also has been approved and is on the “cusp” of commercialization. Senomyx also has identified a molecule that enhances sugars sucrose and fructose, and has been screening molecules that reduce or block bitter tastes.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.