Early Histogen Study Offers Hope for Retreating Hairlines, Cadence Pharmaceuticals and Vertex Raise Lots of Cash, Unmanned Predator Begins New Air Patrol, & More San Diego BizTech News

to invest in late-stage biotech companies that have cleared their riskiest stage of development.

—After reporting the failure of its Riquent drug candidate for lupus, La Jolla Pharmaceutical (NASDAQ: [[ticker:LJPC]]) says it is evaluating its strategic options for selling or unwinding the business. The biotech says it’s laying off an undisclosed number of employees to reduce costs.

—The unmanned Predator aircraft that General Atomics Aeronautical Systems developed for the CIA and military surveillance was put on a new course in 2005, when the U.S. Department of Homeland Security selected it to patrol U.S. borders. Predators have been flying the boundary with Mexico for years, and now the mission has entered a new phase, as U.S. Customs and Border Protection said last week said it has begun Predator air patrols along the North Dakota border with Canada.

—After gaining decades of experience in aquaculture, Kent BioEnergy is shifting its focus on developing algae for renewable energy, water remediation and other uses. President Jack Van Olst told me the company is pursuing a multipurpose strategy that emphasizes a systems approach and seeks to maximize efficiencies by using algae in many different ways.

—Verenium (NASDAQ: VRNM), a Cambridge, MA, startup that has about 180 employees in San Diego has established a joint venture with BP to build commercial-scale biofuel plants in the United States. Verenium, which was formed in the 2006 merger of Boston’s Celunol and San Diego’s Diversa, uses proprietary microbes to break down sugar cane and other high-cellulose material into ethanol.

—San Diego’s 4-D Neuroimaging, which specializes in magnetoencephelography, or MEG, to detect bio-electric fields in the brain, ceased operations last week—putting an estimated 38 employees out of work. The company’s machines, used mostly in diagnostic imaging of patients with epilepsy, are in hospitals around the world.

—Hercules Technology Growth Capital (NASDAQ: [[ticker:HTGC]]), a specialty finance company based in Palo Alto, CA, has closed its San Diego office and laid off three employees who were employed here.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.