San Diego Celebrates Its Breakout Companies of 2008

 about 80 percent (willpower). We just will shit to happen, and the quality of the idea drives the level of success.”

Sapphire Energy gained wide attention last May when it announced it had proven the feasibility of using algae to produce “green crude” that was chemically identical to crude oil. Sapphire said its algal crude, unlike ethanol, can be transported through the nation’s fuel pipeline infrastructure and can be processed at any petroleum refinery.

Sapphire Energy CEO Jason Pyle predicts his company will begin selling algae-based biofuels in commercial markets in three to five years. “But I think it will be some time before we will make a mark in an industry selling 20 billion barrels a day.”

As for continuing to drive Sapphire’s business development amid the recession, Pyle said, “We’re all scared of things that have happened recently. But empirically, investing in business during an economic downturn has always been the right thing to do. From my perspective, everything has gotten cheaper. For example, putting concrete and steel in the ground has gotten 30 percent cheaper, so my goal is to put a lot of concrete and steel in the ground” in Las Cruces, NM, where Sapphire is building its production facilities.

In announcing Novalar’s first product launch, CFO Robert Stefanovich said its OraVerse dental anesthesia reversal agent was San Diego’s only biotech product to win approval last year from the Food and Drug Administration. “I think we had about a day of celebration after we received FDA approval, and then we started getting calls from our VCs,” Stefanovich said. He told the audience yesterday it is the only drug that reverses the effects of dental anesthesia, which leaves dental patients looking and speaking like Rocky Balboa.

The startup has raised almost $70 million since it was founded in 2000, including about $30 million in late 2007 to fund the anticipated launch of OraVerse.

To support the commercialization of OraVerse, Stefanovich says Novalar hired 28 sales executives to coordinate sales in six key regions of the United States. The company plans to expand its sales and marketing efforts throughout the country in about six months, but right now, Stefanovich says, “We’re going after the top 20 percent of dentists in those regions.”

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.