Universal Healthcare Can Save Money, But Innovation Is Key: My Experiences in Japan and the U.S.

that of the United States.

There is another important contrast in Japan: the institutional approach to healthcare can make innovation and the discovery of breakthrough treatments even more difficult. In the U.S., companies are known for and our industry’s success is driven by an indomitable entrepreneurial spirit. Pharma and biotech leaders strike out on their own and start up new companies to spur growth, explore new technologies and build innovative pipelines focused on cutting-edge (and largely untested) research. This is often not the case in Japan where the corporate culture tends to retain top talent within its hierarchical structure, as opposed to ‘spinning out’ these minds to create the next generation of companies. There are companies in Japan that are innovating, though—for example, Otsuka, one of Japan’s largest pharmaceutical companies has partnered with Acucela, the Bothell, WA-based company I founded in 2002, and together we are working to develop novel, first-in-class treatments for blinding eye disease.

With health care reform pending in Washington, D.C., I think it will be critical that we strike the right balance of providing an institutional structure that provides baseline coverage for everyone in the country while not sacrificing our high quality care. It is also essential to address how any shift in the focus of our current health care system could affect the research, drive and innovation that leads to medical breakthroughs. These innovations are the cornerstone of our industry’s entrepreneurial culture and have the potential to greatly improve the nation’s health and quality of life.

We must keep innovation at the forefront of our minds and our strategies through any health care reform process. To be sure, access to quality health care is critical and a top priority for our country, but we must also remember that our unique American spirit of exploration and entrepreneurship feeds the global need for medical breakthroughs and creates a wealth of effective treatments for all the citizens of the world. We must examine closely solutions that could dampen that spirit or institutionalize innovation – they are assets.

Author: Ryo Kubota

Ryo Kubota is chairman, president and CEO of Seattle-based Acucela. He is an ophthalmologist by training who has performed more than 1,000 eye surgeries. Before founding Acucela in 2002, Dr. Kubota spent his early career performing ocular research at Keio University, where he earned his M.D. and Ph.D. In the course of his work there, he discovered the glaucoma gene, myocilin, a discovery that earned him the Suda Award for his contribution to the field of neurodegenerative retinal disease. Dr. Kubota continued his research at the University of Washington and later licensed his findings from the university as the core technology on which he founded Acucela to develop novel and safe therapies for patients with blinding eye diseases. Dr. Kubota is a member of the American Academy of Ophthalmology, the Association for Research in Vision and Ophthalmology, the Japanese Ophthalmological Society and the Japan Glaucoma Association. He serves on the Foresight Group of the Department of Pharmacology at Case Western Reserve University and on the board of the Japan-America Society.