The San Diego Biotech Survival Index: Local Firms Make Strong Rebound In First Half of 2009

Hollis-Eden Pharmaceuticals (NASDAQ: [[ticker:HEPH]])
Cash on hand: $15.2 million
Previous Xconomy coverage:
“San Diego Biotech Hollis-Eden Terminates CEO”

Illumina (NASDAQ: [[ticker:ILMN]])
Cash on hand: $790 million
Previous Xconomy coverage:
“Illumina Sales Miss Expectations“
“Illumina Shows Its Stuff to Wall Street, Stock Still Slides”

Inovio Biomedical (AMEX: [[ticker:INO]])
Cash on hand: $8.3 million
Previous Xconomy coverage:
“Inovio, Fuelled by Swine Flu Fear, Reinvents Itself as Developer of Universal Flu Vaccines”

Isis Pharmaceuticals (NASDAQ: [[ticker:ISIS]])
Cash on hand: $637.5 million
Previous Xconomy coverage:
“Isis, Genzyme Use Antisense to Go Where Many Drugs Fail, the Brain“
“Genzyme, Isis Cholesterol Drug Reaches Goal in Pivotal Study, Paving the Way to FDA“
“Isis Pharmaceuticals Second Drug Aims to Block Marker of Heart Disease, Inflammation“
“Alnylam, Isis Offspring, Regulus, Keeps Pushing on Biology’s Bleeding Edge”

Life Technologies (NASDAQ: [[ticker:LIFE]])
Cash on hand: $582 million
Previous Xconomy coverage:
“From Merger of Invitrogen and Applied Biosystems, Life Technologies Plans to Grow From San Diego Base”

Ligand Pharmaceuticals (NASDAQ: [[ticker:LGND]])
Cash on hand: $55.5 million
Previous Xconomy coverage:
“Ligand Gets Neurogen for $11 Million“
“Ligand Cuts Another Deal With GlaxoSmithKline”

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Metabasis Therapeutics (NASDAQ: [[ticker:MBRX]])
Cash on hand: $6.6 million
Previous Xconomy coverage:
“Ailing Metabasis Hires Advisory Firm“
“Metabasis Therapeutics Restructures, Cuts 38 From Staff“
“Latest Metabasis Cutbacks Leave Just Seven Employees”

Neurocrine Biosciences (NASDAQ: [[ticker:NBIX]])
Cash on hand: $74 million
Previous Xconomy coverage:
“$75M Financing for Neurocrine
“Neurocrine Cuts Half of Workforce”

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Author: Luke Timmerman

Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.