The San Diego Biotech Survival Index: Local Firms Make Strong Rebound In First Half of 2009

Optimer Pharmaceuticals (NASDAQ: [[ticker:OPTR]])
Cash on hand: $51.2 million
Previous Xconomy coverage:
Optimer Rides Investment See-Saw With Promising Drug for C.Diff Infections
Optimer Sharpens Up Commercial Game Plan After C.Diff Drug Success
Optimer’s Second Drug for Traveler’s Diarrhea Follows Fast Behind Lead C.Diff Antibiotic
Optimer Shares Skyrocket As Drug Halts Deadly Bacterial Infection in Trial

Orexigen Therapeutics (NASDAQ: [[ticker:OREX]])
Cash on hand: $46 million
Previous Xconomy coverage:
Orexigen Aims to Redefine Obesity as Amgen Vet Revamps Company to Compete
Orexigen Drug Hits Weight Loss Goal in Studies, Company Looks Toward FDA
Orexigen Obesity Drug Produces Modest Weight Loss, Lowers Cardiovascular Risk

Quidel (NASDAQ: [[ticker:QDEL]])
Cash on hand: $49.4 million
Previous Xconomy coverage:
Quidel, Pulling Off a Turnaround, Predicts Record Profit on Demand for Flu Tests

Santarus (NASDAQ: [[ticker:SNTS]])
Cash on hand: $57.5 million
Previous Xconomy coverage:
Santarus Takes on Marketing Goliaths With Faster Acting Heartburn Drug
Santarus Nabs U.S. Rights for Two Drugs in Cosmo Collaboration

Sequenom (NASDAQ: [[ticker:SQNM]])
Cash on Hand: $69.3 million
Previous Xconomy coverage:
Sequenom Maintains Tight Lid on Mishandled Data of Key Diagnostic Test
Sequenom, Fueled by Blood Test for Down’s, Aims To Be the Google of Molecular Diagnostics
Sequenom Blood Test Clears Higher Hurdle, Company Plots Aggressive Moves Toward Market

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Somaxon Pharmaceuticals (NASDAQ: [[ticker:SOMX]])
Cash on hand: $1.3 million
Previous Xconomy coverage:
Somaxon Renews Its Insomnia Drug Application, Raises $6m
FDA Rejects Somaxon’s Application for Insomnia Drug

Torrey Pines Therapeutics (NASDAQ: [[ticker:TPTX]])
Cash on hand: $1.2 million
Previous Xconomy coverage:
Wanted at Torrey Pines Therapeutics: Shareholders Who Vote

Vical (NASDAQ: [[ticker:VICL]])
Cash on hand: $49 million
Previous Xconomy coverage:
Vical on Fast Pace With Animal Tests of Prototype Swine Flu Vaccine
After Years of Red Ink, Vical Says DNA-Based Vaccines Ready for Prime Time

Author: Luke Timmerman

Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.