Zogenix Raises Cash for Headaches, Sleepless in Somaxon, Dow Chemical Spins Out Pfēnex, & More San Diego Life Sciences News

From Adamis to Zogenix, we’ve got the A to Z in San Diego life sciences news. Here’s your chance to catch up now.

Zogenix said it has raised a total of $71 million for the anticipated launch in January of its needle-free, drug-and-device delivery system for migraine and cluster headaches. The San Diego life sciences company, which said it had raised $51 million three months ago, disclosed that it had raised an additional $20 million from Chicago Growth Partners.

Nexus Biosystems, a life sciences tools company based near San Diego in Poway, CA, announced plans to acquire Aurora Biotechnologies of Carlsbad, CA, for an undisclosed price. Both companies specialize in the storage and management of biological samples used to study genetic traits and human disease, among other things.

—The FDA’s rejection of an insomnia drug for the second time this year must be keeping some executives awake at night at San Diego’s Somaxon Pharmaceuticals (NASDAQ: [[ticker:SOMX]])). The FDA says that Somaxon’s doxepin (Silenor) wasn’t effective enough to meet the agency’s standard for approval.

—Luke profiled Scott Forrest, the 32-year-old director of business and technology development (i.e. tech transfer) at The Scripps Research Institute. Since joining Scripps 10 months ago, Forrest says his goal is to do a better job of spinning out its renowned biomedical science into startup companies, as well as its potential drug candidates that might someday be commercialized.

—There’s a new biotech in town, Pfēnex, which was spun out by Dow Chemical with venture backing from Signet Healthcare Partners. The San Diego biotech specializes in developing a variety of protein-based drugs, vaccines, diagnostic reagents, and biosimilars using technology derived from a bacteria that secretes a fluorescent pigment.

Adamis Pharmaceuticals of Del Mar, CA, has agreed to a merger with San Diego’s La Jolla Pharmaceutical, which recently dropped efforts to get its shareholders to approve its liquidation plan. Under a reverse merger by the boards of both companies, La Jolla Pharmaceutical shareholders will get as much as a 30 percent ownership of the combined company.

—Luke described the work of Tony Manning to develop “bispecific” antibodies at Biogen-Idec, which is based in Cambridge, MA, and operates a San Diego research facility. Manning spearheads a group that is engineering a new class of antibodies to hit two disease targets on cells, not just one.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.