My Top 10 List of Innovations Across the Spectrum

Here are my top 10 innovations that are coming to the forefront in 2010. Of course, none of these would be possible without the economic engine that is embodied by the USA Science & Engineering Festival, which is creating the innovative minds of the future.

1) High-tech treatment of nuclear waste, a technology that solves the key bottleneck to new nuclear growth and old nuclear cleanup. Example: stealth company Kurion of New York, NY.

2) Coal to Liquid Technologies are the culmination of decades of innovative processes now ready for widespread commercialization. That makes abundant U.S. coal a clean fuel. Example: Accelergy of Houston, TX.

3) LEDs for clean water. Using ultraviolet light emitting diodes (LEDs), which operate at 265nm—the optimum wavelength for germicidal disinfection—represents a breakthrough in water purification. Example: CrystalIS of Green Island, NY.

4) Nanotechnology is transforming cancer treatment by using precise targeting of out-of-control cells, which limits the harsh side-effects of poisoning people with chemotherapy and burning them with radiation. Example: Cerulean Pharma of Cambridge, MA.

5) Rapid Vaccine discovery. Quickly evolving antigens need quickly evolving vaccines. Example: Genocea Biosciences of Cambridge, MA.

6) Wireless TV & Video at 60GHz cuts the cords and the messy morass of connecting wires to create higher quality in-room wireless video area networks. Example: SiBeam of Sunnyvale, CA, with offices in San Diego, Tokyo and Seoul.

7) Efficient data centers at light-speed. By integrating high-performance optics directly with silicon-based electronics, it is possible to bring “fiber to the chip” connectivity to market. Example: Luxtera of Carlsbad, CA.

8) Touch-screens so cheap they’re disposable. Nanostructured materials offer display devices and components with enhanced performance at a lower manufacturing cost. Example: Cambrios of Sunnyvale, CA.

9) Powerless Memory, using the magnetism of electron spin. Technology innovation makes it feasible to store information in magnetic material integrated with silicon circuitry to deliver the speed of SRAM with the non-volatility of Flash. Example: Everspin Technologies of Chandler, AZ.

10) Bio-algae produced fuels. Using the tools of modern biotechnology to identify and optimize strains of algae for the production of biological oils as a substitute for petroleum-based crude oil. Example: Sapphire Energy of San Diego.

[Editor’s Note: As the decade comes to an end, we’ve asked Xconomists and other technology leaders around the country to identify the top innovations they’ve seen in their fields the past 10 years, or predict the top disruptive technologies that will impact the next decade.]

Author: Larry Bock

In Memoriam: Our friend and Xconomist Larry Bock passed away on July 6, 2016. We at Xconomy are deeply saddened by his loss. Larry Bock is the founder and organizer of the USA Science & Engineering Festival, and a former founder of the San Diego Science Festival. Mr. Bock is a Special Limited Partner to Lux Capital, a $100M nanotechnology-focused venture capital fund. He is a member of the Board of Directors of FEI Corporation (NASDAQ: FEIC), the leading supplier of tools for nanotechnology research. He is a General Partner of CW Ventures, a $100M life sciences venture capital fund. Mr. Bock was the founder and former executive chairman and initial CEO of Nanosys and the founder and initial CEO of Neurocrine Biosciences (NASDAQ: NBIX), Pharmacopeia (NASDAQ: PCOP), GenPharm International, which was acquired by Medarex for $100 million; Caliper Technologies (NASDAQ: CALP); Illumina Technologies (NASDAQ: ILMN), among numerous other firms. He was also a seed or early-stage investor in variety of firms, including Acceleron Pharma, Aurora Biosciences, Biosym Technologies, ekoVenture. Gen-Probe, Gensia Pharmaceuticals, Genocea Biosciences, IDEC Pharmaceuticals Magen Biosciences, Oclassen Pharmaceuticals Plexikon Pharmaceuticals, Poland Partners, Sequana Therapeutics, Sapphire Energy, Siluria, Sirtris Pharmaceuticals, Software Transformation, and Viagene. Mr. Bock started his career as a researcher in the early days at Genentech, the field of infectious diseases, where he was on the team that received the AAAS Newcomb Cleveland Prize for demonstrating the world’s first recombinant DNA vaccine. He was a Venture Capital Associate with Fairfield Ventures (now Oxford Bioventures). Larry and his wife, Diane, established the Larry and Diane Bock Chair in Nanotechnology at the University of California, Berkeley. They also founded Community Cousins, a non-profit foundation focused on breaking down racial barriers, that was selected by former Vice President Al Gore as one of 10 outstanding grass root efforts nationally. Larry is organizing the San Diego Science Festival with BioBridge of UCSD. He works extensively with the Sudanese and Burmese refugee’s networks in San Diego and is a tutor in math and sciences for Sudanese refugee children in St. Lukes Sudanese Refugee Network and a Mentor for Burmese refugee families through Jewish Family Services. Larry received his B.A. in Biochemistry (summa cum laude) from Bowdoin College and his M.B.A. from the Anderson School at UCLA.