Don’t Listen To Your Critics, VCs Are Not Enough, and Other Lessons from Breakthrough Idea Forum

turning big companies’ strengths into weaknesses. And Myhrvold emphasized that failure is inevitable if you’re taking risks, but “you have to have a business model that can sustain that.”

5. Put the right team and culture in place. This is nothing new, but when it comes down to executing on breakthrough ideas, it is the most important factor. “The key is getting the right CEO,” Hood said. “And get focused. The biggest destroyer of young startups” is trying to do too many things, he said. (This is an example of a common principle governing both tech and biotech startups.)

Here are some thoughts on the deeper dives into potential breakthrough ideas that we heard at the event:

—Christina Lomasney from Seattle-based Modumetal showed how nanomaterials grown in a novel way could change the entire metals industry. It is already having an impact on defense and industrial applications. One question is whether the technical process (and the business) will scale up to handle mainstream applications in energy efficiency, transportation, and manufacturing.

—Mick Mountz of Boston-area Kiva Systems dazzled the crowd with videos of mobile robots moving inventory around in warehouses to improve the logistical efficiency of retail distribution. This got a lot of interest, especially given the strengths of the Seattle area in e-commerce and retail.

Steve Seitz of UW computer science and engineering (and Google) showed how computer vision techniques can be used to do things like build 3-D virtual environments from the world’s Flickr photos, and produce smooth imaging sequences of your kid’s face as she grows up.

—Bill Bryant of Draper Fisher Jurvetson outlined his firm’s philosophy of investing in “brave new world” startups that don’t just provide 10 times more value than the status quo, they strive to create new industries. Bryant argued that DFJ takes risks and invests in potential breakthrough ideas (such as Synthetic Genomics, Tesla Motors, Space X, and locally, Redfin and Opscode).

—Norm Wu from Seattle-based Qliance tantalized the crowd with his vision of primary care without health insurance companies, which is already working on a relatively small scale. One question is whether Qliance can scale up its business to handle all of middle America

Author: Gregory T. Huang

Greg is a veteran journalist who has covered a wide range of science, technology, and business. As former editor in chief, he overaw daily news, features, and events across Xconomy's national network. Before joining Xconomy, he was a features editor at New Scientist magazine, where he edited and wrote articles on physics, technology, and neuroscience. Previously he was senior writer at Technology Review, where he reported on emerging technologies, R&D, and advances in computing, robotics, and applied physics. His writing has also appeared in Wired, Nature, and The Atlantic Monthly’s website. He was named a New York Times professional fellow in 2003. Greg is the co-author of Guanxi (Simon & Schuster, 2006), about Microsoft in China and the global competition for talent and technology. Before becoming a journalist, he did research at MIT’s Artificial Intelligence Lab. He has published 20 papers in scientific journals and conferences and spoken on innovation at Adobe, Amazon, eBay, Google, HP, Microsoft, Yahoo, and other organizations. He has a Master’s and Ph.D. in electrical engineering and computer science from MIT, and a B.S. in electrical engineering from the University of Illinois, Urbana-Champaign.