Affymax Tanks on Anemia Results

Affymax (NASDAQ: [[ticker:AFFY]]), the Palo Alto, CA-based developer of an experimental anemia drug, released some bad news today from clinical trials conducted with partner, Takeda Pharmaceuticals. While four pivotal studies of a combined 2,609 patients showed that peginesatide (Hematide) wasn’t inferior to competing products from Amgen in terms of boosting hemoglobin to carry oxygen in the blood, researchers did see a higher combined rate of adverse cardiac events like heart attack, stroke, heart failure, and death in a group of patients on the new drug. The cardiac effect was seen among anemia patients who aren’t on kidney dialysis, a potentially huge market for any anemia drug. Shares of Affymax plunged 65 percent to $8.06 by 9:15 am Eastern in pre-market trading.

Author: Luke Timmerman

Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.