Illumina Acquires Helixis for Up to $105M, To Get Small, Low-Cost Genetic Analysis Tool

San Diego-based Illumina has acquired an intriguing startup from southern California with a vision of putting low-cost genetic analysis systems on every biologist’s benchtop.

Illumina (NASDAQ: [[ticker:ILMN]]), the leading maker of high-speed gene sequencing instruments, said today in its second-quarter financial report, and in a separate statement, that it has acquired Carlsbad, CA-based Helixis for $70 million in cash upfront, plus another $35 million in contingent considerations. Helixis CEO Alex Dickinson has agreed to join Illumina as a senior vice president, and assist in the coming weeks with the introduction of a new product line Illumina is calling Eco Real-Time PCR.

The acquisition was apparently made on April 30, but wasn’t announced until today’s quarterly report. Still, the Helixis deal shouldn’t come as a surprise, given that Illumina CEO Jay Flatley joined the startup’s board last year as it prepared to launch its new product for high-powered, low-cost polymerase chain reaction (PCR) testing. Helixis, which I profiled back in January, was built around the idea creating a real-time PCR technology that’s small enough to sit on the average lab bench, costs less than one-fourth of the standard bulky machines found in centralized labs, and performs with a higher degree of accuracy and consistency. Helixis, which began with technology developed in the Caltech labs of David Baltimore and Axel Scherer, wanted to make a lab bench tool that any biologist could use to precisely measure how DNA is switched on or off in a given sample of, say, cancer cells, compared with healthy cells.

While the big standard machines sold by competitors like Life Technologies, Bio-Rad Laboratories, and Roche can cost as much as $50,000, the new Illumina tool aims to carve out a new market at a much lower price—$13,900. That price should make it “accessible to individual researchers around the world,” Illumina said in a statement.

“We are excited to launch the Eco Real-Time PCR System, which we believe will set new standards for performance, simplicity and affordability,” said Christian Henry, Illumina’s senior vice president and general manager, life sciences, in a statement.

Helixis’ investors appear to be getting a pretty good return on their investment. The company was founded in 2007 with a $10 million investment from Domain Associates, Advanced Technology Ventures, and Okapi Venture Capital. Back in October, Xconomy reported on a regulatory filing which showed the company had raised another $7.3 million.

Author: Luke Timmerman

Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.