San Diego’s Zogenix Moving Fast to Commercialize Drug-and-Device Combo

needle-free drug delivery technology that was being developed for use with sumatriptan, a fast-acting migraine drug, by Hayward, CA-based Aradigm. Hawley, who was familiar with migraine drugs from his years at Glaxo, led the acquisition of the Aradigm technology. Aradigm’s Stephen Farr, who had led development of the technology at Aradigm, joined Zogenix as a co-founder, president, and chief operating officer.

“It’s not that unusual, really,” Hawley says. Garner “is kind of a serial entrepreneur. He often picks the management team first… It starts small, and if you’re in the pharmaceutical business it quickly gets to be a very large amount of money.”

Despite Hawley’s modesty, Zogenix didn’t really start small. Its Series A round came to a whopping $60 million, with Clarus Ventures, Domain Associates, BA Venture Partners (now Scale Venture Partners), Thomas, McNerney & Partners, and Life Science Angels chipping in; the round later expanded to $78 million. Zogenix filed for an IPO in 2008, but market conditions led the company to cancel those plans. That necessitated last December’s Series B round of $71 million, which was extended in July to include an additional $15 million in equity and $35 million in debt financing. Additional investors include Abingworth Management, Chicago Growth Partners, with Oxford Finance Corp. and Silicon Valley Bank providing the debt facility.

“Actually, our story hasn’t changed since we formed the company, which is something we’re proud of,” Hawley says. They first planned to validate the technology now being marketed as Sumavel DosePro and win FDA approval as a

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.