How Bay Area Biotech Stacks Up With the Rest of the World

because of our intimate relationship with innovation. Our IP policies are very strong. The local tech transfer offices at Stanford, UC San Francisco and UC Berkeley have led to incredible technological breakthroughs. Such innovations have paved the way for Mission Bay’s growth and the development of the California Institute of Regenerative Medicine.

Unfortunately, based on California’s state rankings on K-12, we may well trail the US’s mediocre score in Education and Workforce. More needs to be done to position our current and future workforce for success. California’s student performance continues to rank in the bottom quartile in science and the third quartile in math. Although our region attracts a disproportionally high number of foreign graduate students, we need educational conditions that will foster local talent.

While our local community receives high marks for venture capital investment, it is not a business friendly environment. According to the 2010 State Business Tax Climate Index, California ranked 48th and for the fourth year in a row the nation’s CEOs ranked California rock bottom in the 2009 Best & Worst States survey for Chief Executive Magazine. For this, I would give Enterprise Support much lower marks. The State’s inability to maintain the 20-year Net Operating Loss carry forward, the Singles Sales Factor corporate tax apportionment formula and several other tax provisions available to biotech companies elsewhere significantly inhibits our region’s score.

Arguably, you will find no other greater concentration of biotechnology than in Northern California, the birthplace of biotechnology. We stand arm-in-arm with San Diego and Boston/Cambridge. More than 1,300 companies employ more than 100,000 people in intensive R&D activities. In addition, four academic research institutions receive more than $500 million annually in research funding. Northern California should be ranked well above the national average in Intensity. However, the rapid development of biotech clusters in other countries, as quantified in the Worldview Scorecard, is a good wake-up call that we cannot take our current leadership for granted much longer. We must actively support our industry.

The Worldview Scorecard is a useful tool for assessing and prioritizing our efforts at BayBio. In the chart above we have identified our major programs (and events) that support each of the five pillars. We will continue to use this tool to assess our performance. We are trying to address our standing in the world and correct the items that matter to our community. We welcome your thoughts on what else we should be doing. Email us at [email protected].

[Editor’s Note: A version of this editorial was first published in BayBio’s electronic newsletter.]

Author: Gail Maderis

Gail Maderis is President & CEO of BayBio, the industry organization representing and supporting Northern California’s life science community. As a former biotech CEO, Ms. Maderis brings deep experience and commitment to supporting the industry through enterprise development, peer-to-peer experience sharing, advocacy and support of education and workforce development. From 2003 to 2009, Ms. Maderis served as President and CEO of Five Prime Therapeutics, Inc., a privately held protein discovery and development company. At FivePrime, she successfully funded the company’s rapid growth through substantial private equity financings and corporate partnerships and took the company’s first novel cancer therapeutic from discovery into clinical trials. Prior to FivePrime, Ms. Maderis held senior executive positions at Genzyme Corporation, including founder and president of Genzyme Molecular Oncology (GZMO). Ms. Maderis practiced management and strategy consulting with Bain & Co. She serves on the boards of BayBio, the Mayor’s Biotech Advisory Council of San Francisco and the HBS Healthcare Initiative. She received a BS in business from the UC Berkeley and an MBA from Harvard Business School.