A SBIR Program Director Offers Insights in Small Business Innovation Research “Grantsmanship” in the Life Sciences

There was a heavy turnout among rank-and-file scientists when the grassroots San Diego Entrepreneur Exchange (SDEE) hosted a panel discussion earlier this year on how to win a Small Business Innovation Research (SBIR) grant.

So it might be standing room only for the briefing that San Diego’s Biocom industry group has organized tomorrow at the Mintz Levin law firm, with presentations by the top administrators of the National Cancer Institute’s (NCI) SBIR Development Center. In recent years, the center has launched a variety of new initiatives aimed at the funding needs of life science startups and intended to help commercialize new technologies for diagnosing and treating cancer. Perhaps foremost is the Phase II Bridge Award program, which can provide as much as $3 million over three years—triple the $1 million funding limit usually set over a two-year period for Phase II awards.

With venture capital funding still at a low ebb following the market collapse of 2008, applications for Phase I funding (a maximum of $150,000) under the SBIR program increased by 68 percent from 2008 to 2009, according to GenomeWeb.

In recent years, the federal government has been awarding a total of more than $2.2 billion a year in funding for SBIR and Small Business Technology Transfer (STTR) grants—with the NCI getting about $110 million of the $616 million total allotted to the National Institutes of Health in 2010, according to Ali Andalibi, program director of the NCI SBIR Development Center.

“What’s changed is the way the program is administered,” Andalibi told me in a recent telephone interview. In creating the SBIR development center in 2008, Andalibi said the NCI was emulating the National Science Foundation by creating a centralized program office to manage all aspects of the cancer institute’s SBIR and STTR programs. As an example of the sort of innovation needed, the NCI and other NIH institutes recently issued a SBIR contract solicitation in search of 

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.