5 Biotech Storylines to Watch in Boston

Alnylam Pharmaceuticals, a leading developer of RNA interference drugs, prompting Alnylam to announce a 25-30 percent reduction in its work force last month. The field might need a breakthrough in drug-delivery technology to boost confidence that RNA interference will live up to its promise.

4. More Changes at Biogen Idec

Weston, MA-based Biogen Idec, one of the world’s largest makers of multiple sclerosis drugs, has a new CEO, George Scangos, who might shake things up at the company. When he took the job in June, he said that he would review the firm’s R&D strategy and would look to make changes. The new boss hasn’t provided details on those changes yet, but he told the Boston Globe last week that he plans to unveil a new operating blueprint by the end of the year. As we reported on July 1, Scangos has indicated that his changes could mean that certain R&D programs get shed from the pipeline. We’ll be watching for what the expected changes will mean for Massachusetts’s second-largest biotech firm.

5. Campaign Against Cancer

My colleague Luke did a great job of summing up this ever-unfolding story in his recent post about Xconomy’s next biotech forum called Boston’s War on Cancer. With more than half a million Americans dying from cancer every year, many Boston-area biotech firms have a lot riding on the success of their experimental cancer drugs. For instance, Cambridge-based Ariad Pharmaceuticals (NASDAQ:[[ticker:ARIA]]) is expected to report data later this year from its pivotal study of a drug called ridaforolimus for treating certain forms of soft tissue and bone cancer. So stay tuned…

Author: Ryan McBride

Ryan is an award-winning business journalist who contributes to our life sciences and technology coverage. He was previously a staff writer for Mass High Tech, a Boston business and technology newspaper, where he and his colleagues won a national business journalism award from the Society of American Business Editors and Writers in 2008. In recent years, he has made regular TV appearances on New England Cable News. Prior to MHT, Ryan covered the life sciences, technology, and energy sectors for Providence Business News. He graduated with honors from the University of Rhode Island in 2001 with a bachelor’s degree in communications. When he’s not chasing down news, Ryan enjoys mountain biking and skiing in his home state of Vermont.