Life Technologies’ CEO Talks Strategy, Phenomix Falls, Arena Pharmaceuticals Grapples With FDA Setback, & More San Diego Life Sciences News

From the shutdown at Phenomix to the strategy insights shared by Life Technologies’ Greg Lucier, it was a big week for life sciences news. Get your update here and now.

—The shot was fired back in April, but the wound proved fatal to Phenomix by the end of September. San Diego-Phenomix laid off its workforce and went out of business five months after Forest Laboratories terminated its support of clinical trials for dutogliptin, an experimental drug for diabetes.

—Life Technologies (NASDAQ: [[ticker:LIFE]]) chairman and CEO Greg Lucier was the headliner in a discussion about the future of personalized genomic medicine, and he delivered some compelling insights about the Carlsbad diagnostics equipment maker’s strategy. Lucier said Life is on its way to becoming a big medical company over the next two years, as well as a big supplier of research equipment and materials. Something is working right, since the company’s third quarter revenue increased 83 percent year-over-year, and Life said its third-quarter net income of $105.6 million (or 56 cents a share) showed a 156 percent gain over the same quarter last year.

Complete Genomics, a Mountain View, CA, company developing low-cost gene sequencing technology, plans to raise as much as $96.6 million in its IPO, which is scheduled for the week of Nov. 8. Complete Genomics (which is backed by San Diego’s Enterprise Partners and other investors) is among a handful of companies, including San Diego’s Illumina and Life Technologies of Carlsbad, CA, that are driving down the cost and time required to sequence entire genomes.

—San Diego’s Arena Pharmaceuticals (NASDAQ: [[ticker:ARNA]]) is trying to regroup after the FDA turned down Arena’s application to market a new drug (lorcaserin) to help people in the U.S. lose weight. Arena CEO Jack Lief told analysts in a conference call Monday that it was too early to give clarity on the timing of a revised application.

—San Diego’s aTyr Pharma raised $23 million in a venture financing round led by Domain Associates. Since it was incorporated in 2006, aTyr has raised a total of about $46 million from Domain and its other investors: Alta Partners, Cardinal Partners, and Polaris Venture Partners.

Minnow Medical raised a total of $4.7 million through two separate financings, roughly a month after moving the medical device company’s headquarters from San Diego to Laguna Hills, CA, and three months after naming Raymond W. Cohen as CEO. Minnow has been developing a proprietary angioplasty balloon catheter that can be heated to “denature” the hardened fatty buildup that clogs blood vessels. The company is planning clinical trials in Europe next year.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.