Amylin Suspends Obesity Drug Development, Sapphire Energy Partners with Monsanto, 23andMe Gets Connected to UCSD’s Fowler, & More San Diego Life Sciences News

On this St. Patrick’s Day, it seems only appropriate to lead our roundup of biotech news with an item from San Diego’s Sapphire Energy, the algal biofuels startup using biotech tools to develop emerald-green crude. We’ve got the rest of the life sciences news too, as well as a hearty “Top o’ the morning” to you.

—San Diego biofuels startup Sapphire Energy signed a strategic partnership with Monsanto, the agricultural chemical specialist based in St. Louis, MO. Sapphire Energy said it is already in the business of identifying valuable traits for the use of algae in commercial agriculture, and plans to share information with Monsanto on stress tolerance, yield enhancement, and other traits.

Genomatica, the San Diego sustainable chemicals company, forged a strategic partnership with the U.K.’s Tate & Lyle. Genomatica plans to use a Tate & Lyle high-fructose corn syrup plant in Decatur, IL, to make commercial-scale quantities of “Bio BDO,” an intermediate chemical also known as 1,4-butanediol that is used to make spandex, running shoes, automotive plastics, and other consumer products.

—San Diego’s Amylin Pharmaceuticals and Takeda Pharmaceutical of Japan said they suspended a mid-stage clinical trial of an obesity drug candidate that combines two synthetic hormones. The drug companies said they want to investigate new antibody-related laboratory findings from a previous obesity trial involving metreleptin, one of the synthetic hormones.

—I talked with James Fowler, a professor of medical genetics and political science at UC San Diego about his research into social networks and Connected, the book he wrote with co-author Nicholas Christakis of Harvard. Since the book was published, Fowler said he’s done some work for 23andMe, the personal genomics company based in Mountain View, CA. “They realized that in order to provide information about genetics that you need to know something about the social environment as well,” Fowler said.

—The San Diego-based Polaris Group said it is expanding its leadership in conjunction with the advance of the company’s lead cancer drug candidate into late-stage clinical trials. Polaris named former Arena Pharmaceuticals CFO Robert E. Hoffman as its chief financial officer as it moves forward into trials of ADI-PEG 20, a drug developed to treat hepatocellular carcinoma.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.