ITherX Repurposes Kemia Drug

San Diego’s ITherX Pharmaceuticals has begun enrolling liver transplant patients in an early stage hepatitis C trial that seeks to repurpose a drug that was initially under development for treating inflammation. ITherX, with backing from Easton Capital and others, acquired the experimental compound from San Diego-based Kemia in 2009 for $75,000, according to VentureWire. In a proof-of-concept trial that began earlier this month, ITherX says it is testing whether the compound can help prevent the hepatitis C virus from infecting the transplanted liver. Kemia, which discovered the molecule, halted development after the drug failed a mid-stage trial for rheumatoid arthritis.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.