As Kinsella Affair Goes Global, Sofinnova’s Papiernik Says Don’t Blame Big Pharma for Weak Biotech Ventures

Big Pharma has maintained radio silence since Avalon Ventures’ Kevin Kinsella launched a verbal attack last month on what he called the industry’s “predatory business practices,” saying they are doing “enormous damage to the life sciences venture capital ecosystem.” The San Diego biotech investor, in an exclusive interview with Xconomy, argued that pharma’s brass-knuckled M&A tactics are pushing life science ventures “almost to the point of extinction.”

In San Diego, Kinsella’s throwdown prompted the San Diego Venture Group to organize an April 19 debate over the merits of the longtime investment model for life sciences startups. The local venture group recruited Canaan Partners’ Wende Hutton and Versant Ventures’ Camille Samuels to make the affirmative argument for equity investing in biotech, while Avalon’s Kinsella and Frazier Healthcare’s Robert More will take the “con” side of the question.

Kinsella’s critique also hit a nerve on the far side of the world—felt by Antoine Papiernik, a managing partner in the Paris offices of Sofinnova Partners, established in 1972 as the first venture capital firm in France. Of L’Affair Kinsella, or perhaps Le Provocateur Kinsella, Papiernik told me recently via Skype, “One should not accuse the other, finger-point, [saying], ‘It’s you, the pharma, who is destroying the biotech industry.’ Bullshit.”

Sacrebleu! Such words.

Papiernik says Kinsella might have good reasons for his tirade. But the French VC contends the pharmaceutical industry’s bargain-hunting strategy is predictable, given the incredibly weakened state of biotechs and their venture backers today. And he says you can’t blame that on Big Pharma.

What follows is a transcript of our conversation, which has been condensed and edited for clarity:

Antoine Papiernik: [Kinsella] is blaming the pharma industry for something that, well OK, maybe something [was] coming from pharma. But I see it mainly as a rapport de force, a balance of power, and the balance of power has been skewed in favor of pharma.

At the same time, if you think back over the past 15 years, our business is much, much better. As a venture capitalist backing biotech companies, I say it’s much better than it ever was. We have the proof in the pudding. We can say that we have managed to bring NDAs [new drug applications], new products, to the market, things that pharma has been very poor in doing.

So, “A,” we have been incredibly successful as an industry, [especially] if you look at things in comparison with pharma. And “B,” and most importantly in the last 15 years, the pharma [industry] has totally, totally been reshaped. Look at Pfizer today, this is just humongous change among

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.