The Kinsella Debate Continues over Pharma versus Biotech, Worlds in Collision

their resources on easier bets with lower risks, by focusing on late-stage drug development, orphan drugs, and so called “me too” drugs that improve on existing compounds, or repurpose existing drugs for a different use than the FDA approved.

Kinsella says that during a recent dinner with a dozen biotech venture capital leaders, not one “was willing, from an investment thesis perspective, to build a bridge halfway across the chasm. “That other partner in the old days was pharma, and they’re just not there for you any more,” Kinsella says. “They want to beggar your investment thesis and grind you to the bone, or walk away from a deal. The default assumption today is that if you need a pharma company to step into your shoes at any point prior to Phase 3, it’s almost guaranteed that you’ll get a crappy deal. So why would any biotech investor or biotech executive want to beat their head against the wall?”

If you are a venture capitalist or you’re in biotech and you have a crappy deal on the table, you’ll have to ask yourself if it’s better than nothing—and “Yeah, probably, it is almost certainly better than nothing,” Kinsella says. “But if you’re a VC, is that a deal, or are a series of deals like that going to establish your reputation as a competent investor? Hell no.”

If you think of venture capital investing as a pure financial asset play, where VCs are just investing in biotech, or high tech, green tech, or social media, Kinsella says, “venture capitalists don’t need the biotech industry. They’re perfectly jolly making money however they can. But pharma needs products. Pharma needs the biotech industry.”

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.