SF’s Prescience Sharpens New Biotech Business Model in San Diego

hospitalized somewhere between Beijing and Hong Kong for two to three months. “They knew I had meningitis, but they couldn’t figure out what else I had,” she recalls. “They said they didn’t think I was going to make it.”

Richter remembers thinking, “How can we send men to the moon but not be able to figure out what’s wrong with me?”

Her eventual recovery prompted Richter to think about how she wanted to spend the rest of her life. During her years at Nortel, Richter says she was involved with acquisitions, strategic planning, marketing, contract negotiations, engineering and manufacturing optimization, and general management of an IT business. And she remembers thinking, “I am not a scientist, but I am a good businesswoman. There must be a better way, a way to this [to advance new medical discoveries] that is faster, cheaper, and easier.”

With her management of the San Jose BioCenter, Richter began to develop a new model by assuming responsibility for the business operations of all the life sciences startups in the incubator. “Let’s tell these founders, ‘Hey, you’re a scientist. You should just focus on the science, because all the other stuff is just a commodity service, and we’re really good at it.”

When a group of scientific entrepreneurs decide to build a life sciences startup, Richter says they typically find that there’s no such thing as a small commercial space. They usually have to sign a long-term lease for far more laboratory space than they really need. Then they have to go shopping for all the equipment they’ll need—laboratory supplies, biosafety hoods, refrigerators, centrifuges. And then there are all the specialized needs, such as finding a source of reverse osmosis de-ionized water.

Richter says Prescience takes on these business tasks and more. After flooding from a chemistry lab inundated a small startup’s space in the San Jose BioCenter, Richter says Prescience moved the company into another suite and took over the cleanup and lab re-certification process.

“When you look at all these pieces, you can see why it takes a lot of time and a lot of money,” Richter says.

One San Diego startup CEO, G. Sridhar Prasad of CalAsia Pharmaceuticals, tells me, “The overall concept is excellent and will be extremely beneficial for startups that have deep pockets to start with.”

But Prasad says he worries the rent would be too steep for an early stage startup like his, which depends on grants from the National Institutes of Health. He says he also frets about keeping his proprietary information confidential in an incubator’s shared work spaces, and about the experience and qualifications of firms hired to operate sophisticated biomedical instruments.

[Updated to clarify terms.] Richter says she did not address pricing during a December 1 presentation at Janssen Labs. While Prescience has not yet disclosed pricing for the San Diego incubator, Richter says the firm has been developing a series of package prices that are intended to be affordable for life sciences startups, depending on the space and scientific needs of each company.  She also says Janssen Labs has a variety of safe and secure spaces to accommodate companies of varying sizes, so that companies can keep their confidential data and intellectual property secure. As part of Janssen Labs standard operating procedures, she says company employees must be trained to use the common area equipment, or they must use technicians with that expertise.

“Early stage funding in general has been taking a hit, and the life sciences in particular,” Richter says. “Because life science is so risky, a lot of venture capital has pulled out, but now you have different business models coming out. It’s changing the dynamic.”

In the meantime, Richter says she’s working to apply some of her experience in San Jose to help get the Janssen Lab incubator ready to open by next month. She also says she is encouraged by the life science sector’s “cohesive and collaborative community” in San Diego. “We just need to make these investments look a lot more attractive to VCs,” she says, “and to get everybody to beef up their activity in this area again.”

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.