In Life Sciences Partnerships, You Must be Smart from the Beginning

Trius Therapeutics (NASDAQ: [[ticker:TSRX]]) and Bayer, and both parties are going to spend a ton of money, and both parties are going to share certain responsibilities…and managing that relationship is much more than that management team anticipated.”

—Partnerships often lead to acquisitions, but Latham’s Wehrli says that doesn’t mean they’re equivalent. While there can be little difference between “renting” and “buying” a company in this economy, Wehrli says, “What I always counsel clients is that if you’re going to negotiate a partnering deal and a M&A transaction at the same time, you’re going to cannibalize both.”

—Another potential pitfall lies with venture backers who push early stage biotechs into premature partnership deals. Ulrich says VCs often want to “offload their development costs and seek third-party validation to help justify the [lower] valuation in a down round.” Johnson agrees, saying, “They get tired of putting money into these companies, and they start having these discussions about partnering, and of course the biotech CEO goes for that.”

—In short, as Neurocrine’s Gorman puts it, “You have to be smart from the beginning, but you can’t foresee everything. When we decided to focus on women’s health, we saw Wyeth as a natural partner. But by the time we got there, Wyeth was no longer a women’s health company. In fact, it didn’t even exist any more.”

Somehow, Neurocrine still managed to reach a deal with Abbott Laboratories that was valued in 2010 as high as $575 million for global rights to Neurocrine’s experimental drug for endometriosis, a painful condition in which uterine tissue grows outside the womb.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.