San Diego’s Aragon Raises $42 Million, Targets Hormone-Driven Cancers

the estrogen receptor, but also causes it to be degraded, Heyman says.

With the hefty, $42 million round announced today, Aragon says it has raised a total of $72 million since 2009. As Aragon sought to raise its Series C funding, Heyman tells me, “We wanted an investor that had both deep pockets as well as potential links to hedge funds, private equity, or even [help us move toward] an IPO.”

The Topspin Fund should more than satisfy that criteria, Heyman says. It was founded in recent years by Jim Simons, founding CEO of the New York hedge fund Renaissance Technologies, and two other investors, Leo Guthart and Steve Winick.

In a statement from Aragon says, “The addition of an investor like Topspin with a like-minded vision and considerable financial resources strategically provides Aragon with access to significant capital in the future. We are also tremendously excited about the progress we’ve made with our pipeline.”

In conjunction with the financing, Aragon says Topspin’s Guthart will join Aragon’s board. Carol Gallagher, who headed Seattle-based Calistoga Pharmaceuticals before it was acquired last year in a $600 million deal with Gilead Sciences (and a San Diego Xconomist), also is joining Aragon’s board as an independent director.

In Aragon’s statement, Simon is quoted as saying, “The combination of Aragon’s high-quality management team, strong investor base, and its novel insights into two of the most-validated targets in oncology make the company an attractive investment.”

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.