The Thinking Behind Domain’s $760M Life Sciences Deal in Russia

The partnership that the life sciences venture firm Domain Associates and the Russian state technology firm Rusnano disclosed yesterday began almost two years ago, at a time when the U.S. financial crisis was especially bleak.

Domain partner Brian Dovey says he initially conceived of the alliance as a way to tap a new and substantial source of capital for the firm’s portfolio of life sciences companies. “In the beginning, that was kind of the driving force,” Dovey told me last night. “But the more I’ve gotten into it, the more I see the opportunities in developing a medical products company in Russia.”

Domain, which maintains offices in San Diego and Princeton, NJ, and Rusnano, a Moscow-based nanotechnology firm owned by the Government of the Russian Federation, agreed to work together to invest as much as $760 million on both sides of the globe. The deal is intended to provide additional capital for Domain-backed startups in the United States, and to jointly establish a drug and medical device manufacturing facility in Russia.

The agreement calls for Rusnano to invest on a 50-50 basis with Domain and its venture partners in roughly 20 U.S. life sciences companies developing a host of new drugs, medical devices, and diagnostic technologies. Most of the investments would provide crucial late-stage funding for companies already in Domain’s portfolio, although Domain would present Rusnano with investment opportunities in a few early stage deals as well. Either way, Rusnano has agreed to match the amount invested by Domain and its VC partners.

Under a separate-but-related agreement, the startups backed by Domain and Rusnano would grant technology licenses to a manufacturing facility the partners plan to jointly establish somewhere in Russia. The Rusnano plant will make and sell “advanced therapeutic products,” focused chiefly on heart disease, cancer, infectious diseases, wound treatment, and eye disease and target markets throughout Russia, the Ukraine, Belarus, and other members of Russia’s Commonwealth of Independent States.

Russia doesn’t currently have much indigenous pharmaceutical capability, and Dovey estimates Russia now imports

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.