Amylin Booms on Report it Rejected Bristol’s $3.5B Takeover Bid

San Diego-based Amylin Pharmaceuticals (NASDAQ: [[ticker:AMLN]]) saw its shares boom today after it reportedly turned down a $3.5 billion takeover bid from New York-based Bristol-Myers Squibb (NYSE: [[ticker:BMY]]).

Amylin shares rose 48 percent to $22.72 at Noon Eastern time today after Bloomberg News said Bristol privately bid $3.5 billion, or $22 a share, to acquire Amylin. The report was based on two people knowledgeable about the unsolicited offer. Official spokespeople for both companies declined to comment to the news service.

Amylin has endured some rough times of late, most recently because of a troubled alliance with Eli Lilly and a string of regulatory delays for its diabetes drug exenatide (Bydureon). But Amylin’s prospects have significantly improved in recent months. In November, it terminated its collaboration with Lilly, and two months later it won FDA clearance to start selling Bydureon as the first diabetes drug that can be injected as little as once a week. Amylin is facing competition from Novo Nordisk’s liraglutide (Victoza), but escaping the Lilly deal has given it new flexibility to pursue a new marketing partner to help pitch exenatide (Byetta) and the longer-lasting version (Bydureon) around the world.

Tom Russo, an analyst with Robert W. Baird, said today in a note to clients he has forecasted that Bydureon could generate $1.5 billion in sales in 2017, which he said makes Amylin worth $19 a share.

Surely some of today’s stock action is driven by speculation that all this talk of Amylin finding a new marketing partner will end up culminating in some other takeover bid. Bristol-Myers has already made one significant acquisition in the past year, with its $2.5 billion deal to buy Alpharetta, GA-based Inhibitex (NASDAQ: [[ticker:INHX]]), the developer of drugs for hepatitis C.

Author: Luke Timmerman

Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.