Big Data, Big Biology, and the ‘Tipping Point’ in Quantified Health

Applied Proteomics visualisation

overcome to realize this vision, including:

—Scalability. Smarr sees a challenge in developing a bioinformatics network that could expand from a pilot project to serve the health needs of a population as big as San Diego.

—Trustability. As a founding member of Google Health, which operated from 2008 to 2011, Missy Krasner said one issue that became a problem was who owns the data—and who would be the trusted custodian of the data? Krasner, who is now an entrepreneur-in-residence at Morgenthaler Ventures in Mountain View, CA, also asked why anyone would want to participate. “What are the incentives that get the average consumer and the average provider at Sharp or Scripps or anywhere else to actually want to receive that data and do something with it?”

—Profitability. “How do you make money?” asked Lisa Suennen, a co-founder and managing member of the Psilos Group, a healthcare-focused venture capital firm in Corte Madera, CA. “If there’s not a clear path to that, it’s a barrier.”

—Engagability. Generating meaningful feedback for patients will be a challenge, said Ernesto Ramirez, who is working at UCSD’s Center for Wireless and Population Health Systems on a doctorate in health behavior. “To me the issue is not the statistical methods that tell me whether I’m going to have a heart attack. It’s the layering on of all the behavioral methods, the visualization, and all the other ways that you can help me understand the data.”

Despite the thicket of difficulties, though, there are still some things that could be done—which was another recurring theme of the discussion.

“You just start,” said Mark Stevenson, the president and chief operating officer of Life Technologies (NASDAQ: [[ticker:LIFE]]), the global biotechnology company based in Carlsbad, CA. If Larry Smarr’s 10-year experiment in quantified health represents what Stevenson calls an “n of 1”—a single case study—then it’s simply a matter of trying to extrapolate the technology from there to get to an “n of 300,” or an “n of 3 million.”

Rather than trying to

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.