The Recipe for Success Behind Elevation Pharmaceuticals’ $430M Deal

What was Bill Gerhart’s recipe for success at San Diego’s Elevation Pharmaceuticals?

Less than four years ago, Gerhart took a glycoyrrolate, a generic drug approved decades ago by the FDA, and set out to reformulate the compound for use with a nebulizer for chronic obstructive pulmonary disease (COPD), which includes emphysema and chronic bronchitis.

Gerhart persuaded San Diego’s renowned serial entrepreneur Cam Garner and pulmonologist Ahmet Tutuncu to join him. Together they raised $44 million in venture capital, formed an 11-member drug-and-device development team—and voila! They got the buyout offer from Marlborough, MA-based Sunovion Pharmaceuticals yesterday that could eventually be worth as much as $430 million.

“It’s a very important product for Sunovion,” Gerhart told me during by phone yesterday. “It could form the cornerstone for their respiratory product line.”

The deal is a testament to capital efficiency and the lean business model for life sciences startups that has been in vogue in recent years. But is this a recipe that others can follow? Or did an unusual combination of factors come together at Elevation that would enable the VCs to double their money immediately—and perhaps eventually realize a nearly 10x return on investment?

As lead investor Brent Ahrens of Canaan Partners told me by yesterday, the $430 million buyout represents a value creation over the 32 months since Canaan led the Series A round (in January, 2011) that amounts to over $430,000 dollars a day.

Yet Ahrens acknowledged that many of the biggest risks had been minimized when he first looked at

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.