Kinsella Redux: Charting a Way Back for Life Sciences Startups

Avalon Ventures founder Kevin Kinsella

As a man of many talents, Avalon Ventures’ Kevin Kinsella has a tendency to apply a term from one of his fields of interests in a conversation about another.

Kinsella’s career as a biotech venture investor has spanned nearly 30 years and more than 100 financings. These include early stage bets on San Francisco-based Onyx Pharmaceuticals and Aurora Biosciences (now Cambridge, MA-based Vertex Pharmaceuticals) that produced the billion-dollar drugs sorafenib (Nexavar) for treating kidney cancer and telaprevir (Incivek) for hepatitis C.

He’s also had a lifelong love for Broadway theater and is now a Broadway League member (and Tony Awards voter). Kinsella and his wife Tamara were the biggest individual investors in the hit Broadway musical Jersey Boys. They also are among the Jesus Christ Superstar producers who were nominated in May for a 2012 Tony for Best Revival of a Musical.

I’m pleased to note that on October 4, a week from today at the Apella event space at Alexandria Center, the San Diego Xconomist will be taking a star turn at Xconomy’s next big event in New York: Reinventing Biotech’s Business Model for the Big Apple. So when I checked in recently for an update of Kinsella’s showstopper critique of Big Pharma business practices, I was half-expecting him to take a metaphorical detour through Manhattan’s theater district.

Instead, he asked me if I knew what véraison means.

It’s a French viticulture term, and refers to the changing color of grapes as they begin to ripen. As the proud owner of a 12-acre winery in Sonoma County (a purchase made possible by the Kinsellas’ successful investment in Jersey Boys), Kinsella said véraison came to mind because the ideas he expounded last year on overcoming the difficult climate for building biotech companies are now ripening. What that means, he says, is that Big Pharma is finally listening.

“The pharma companies have in unison realized that their actions have jointly and severally done a lot to destroy the

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.