SD Life Sciences Roundup: Organovo, Aethlon, & Deals, Deals, Deals

Biotech laboratory pipettes

the conversion of $2.35 million in debt to preferred stock. San Diego’s City Hill Ventures and LG Electronics USA provided most of the new funding, but Independa did not break out how much investors provided.

—Jeff Behrens, the CEO of Cambridge, MA-based Sialix, talked with freelance writer Juliet Preston about the startup, which moved into San Diego’s Janssen Labs life sciences business accelerator in November. Sialix is developing nutritional supplements and drugs that moderate or inhibit the body’s inflammatory response to a particular sialic acid sugar molecule found in red meat, dairy products, and other foods. Behrens said Sialix also plans to develop drugs that target certain cancers.

—San Diego-based Aethlon Medical, which has been developing a dialysis-like filtration device for straining infectious microbes and cancer particles from the blood, said it has asked the FDA for permission to begin a clinical feasibility study that would use its blood purification device to treat patients infected with Hepatitis-C. Aethlon said its application for an Investigational Device Exemption would allow the use of Aethlon’s “Hemopurifier” to collect the safety and effectiveness data needed to support a premarket approval application.

—San Diego’s Organovo said it is working with researchers at Autodesk to develop 3D design software for Organovo’s bioprinting technology, which lays down a pattern of cultured cells to create bio-engineered structures. In a statement, Organovo said the software development effort represents a major step forward in usability and functionality for designing three-dimensional human tissues, including vital organs like kidneys and bladders.

Domain Associates, the VC firm based in San Diego and Princeton, N.J., said it has invested about $93 million from a $760 million venture fund created last March through a partnership with Russia’s Rusnano. The fund invested $20.6 million in San Diego-based Lithera, a specialist in “aesthetic medicine” developing an injectable drug treatment to selectively reduce fat tissue. The fund also invested $21 million in Branford, CT-based Marinus Pharmaceuticals and $51 million in Regado Biosciences of Basking Ridge, NJ.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.