San Diego Life Sciences Roundup: Evoke Pharma, Isis, Otonomy, & More

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much as $2 million more if they meet certain operating milestones on schedule. The deal was preceded by a series of acquisitions for Accelrys, including the 2012 buyouts of Velquest and Aegis, and the 2013 acquisition of Vialis nine months ago. Accelrys specializes in software that helps organizations better manage their scientific R&D and innovation.

—Shares of Isis Pharmaceuticals (NASDAQ: [[ticker:ISIS]]) have been strengthening since the Carlsbad, CA-based RNA interference drug developer reported interim data from an ongoing midstage trial of its experimental heart drug. The company said its experimental drug ISIS-APOCIIIRx reduced significantly triglycerides in more than 75 percent of the patients tested. The drug is being tested in patients with very high to severely high triglycerides.

Elcelyx Therapeutics, the San Diego diabetes specialist, said it has spun out a separate company called NaZura BioHealth, and provided NaZura with a $5 million credit line to advance development of Lovidia, an over-the-counter dietary supplement meant for weight management. Elcelyx CEO Alain Baron also will serve as CEO of NaZura, and the two companies will share the same board of directors. NaZura intends to

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.