Are Universities Creating Too Many Biotech Startups?

biotech hubs are hubs for reasons.

Discussing factors correlated with success or failure in drug development in Does size matter in R&D productivity? If not, what does?, Michael Ringel of The Boston Consulting Group and colleagues noted, “There was also a significant correlation with success when the company has a major R&D facility present in a science hub—a factor that we believe improves scientific acumen by providing better access to internal talent and to networks for collaboration.”

“Recruiting talented senior management is strongly linked to the success of biotechnology companies,” stated a 2003 paper by Monica Higgins and Ranjay Gulati.

“University spin-offs that receive venture capital funding have a 20% to 26% higher likelihood of commercialization compared with spin-offs that do not,” according to a paper by Christopher Hayter.

As reported in The A-List: The Trend-Shaping Series A Financings Of 2013, the average size of a biopharma Series A was $18 million per company.  How many of the 2012 university biotech startups outside the major hubs will get close to that Series A dollar figure?  If they aren’t getting to that level, are they behind the curve?  Is everyone competing for investment from Jonathan Behr and Phil Murray’s In search of dry powder list?  Alternatively, can university biotech startups outside the major hubs make it with angels and/or other funding sources such as federal Small Business Innovation Research (SBIR) awards? Or are they just at too great of a disadvantage in raising money and recruiting people?

Are universities creating too many life science startups?  Perhaps.

All of which, in my opinion, advocates for a version of Atlas Venture’s seed-led model at universities; de-risk, then scale your winners.  But maybe—probably—consider scaling them in an appropriate hub where it can get the money and the people it needs to grow.

Author: Andrew Steen

Andrew Steen has worked with life science start-up companies since 2000, establishing a broad network of contacts with venture capitalists and individuals involved in R&D and business development in pharmaceutical and biotechnology companies throughout the world. At MetaCyte Andy has played a lead role in creating deal flow. He currently serves on the boards of AnosiaVax, Inc., Gnarus Systems, Inc., Pradama Inc., and TrackFive Diagnostics, Inc., Inc., and was a board member of ImmunoTheragnostics Incorporated until its acquisition in December 2008. Andy has been actively engaged in creating the nascent life science industry in Metro Louisville since joining Louisville Medical Center Development Corporation in 2000. MetaCyte Business Lab emerged from Louisville Medical Center Development Corporation in 2002. Prior to joining LMCDC, Andy spent nearly six years with National City Bank of Kentucky where he held a number of positions, culminating as Senior Credit Analyst/Trainer/Credit Officer providing analyses of a wide variety of industries, including healthcare. Andy holds a B.A. from Transylvania University and an M.B.A. from the University of Louisville. He also attended the University of Kentucky College of Law.