Nonprofit Aims to Boost Early-Stage Healthcare Startups in Milwaukee

The spotlight for healthcare innovation in Wisconsin often falls on the state capital of Madison, and for good reason. The city’s biotech scene has produced a number of successful startups that got acquired or went public, and researchers at its flagship university have for decades made impactful—and at times, incredibly lucrative—discoveries that have fueled a juggernaut licensing and patenting foundation.

But Madison’s success means the public sometimes overlooks the biotech community in the state’s largest metro area, Milwaukee, which features a major GE Healthcare hub, a leading pharmaceutical manufacturer in Cambridge Major Laboratories, and advanced research at several local universities.

“We have unsung heroes (in the Milwaukee area) that are doing good applied science that’s having an impact on society,” says Daniel Sem, a pharmaceutical sciences professor and director of technology transfer at Concordia University Wisconsin, located north of Milwaukee in Mequon.

For Milwaukee’s biotech reputation to rise to Madison’s level, it will require a blockbuster drug discovery (or two) on the scale of the blood thinner Warfarin or vitamin D derivatives from University of Wisconsin-Madison researchers, Sem says. And local advocates believe Milwaukee-area scientists need more help to turn their ideas into commercial successes like these.

That’s why Sem and other local partners have formed Bridge to Cures (B2C), a new nonprofit that will provide mentorship and seed funding to medical entrepreneurs, primarily university researchers spinning out companies. B2C is partnering with Medical College of Wisconsin, University of Wisconsin-Milwaukee, Concordia University, Marquette University, Milwaukee School of Engineering, and BloodCenter of Wisconsin.

B2C will use a “venture philanthropy” model similar to that of BrightStar Wisconsin Foundation, in which any returns from the nonprofit’s startup investments are put back into the fund for future investments, says Sem, B2C’s co-founder, president, and CEO. B2C received $140,000 from Wisconsin Economic Development Corp. and will now seek private donations to match that grant.

The plan is to invest $280,000 total in four local healthcare startups annually. B2C’s strategy will be to help entrepreneurs take ideas in pharmaceuticals, medical devices, and clinical and diagnostic services to the point that they’re ready for venture capital, ideally within three to five years. For example, with drug development, B2C aims to provide seed money and expertise that will help the venture advance from the point of making a discovery that was funded by federal grants to filing an investigational new drug application prior to clinical trials.

After soliciting applications later this year, B2C’s investment committee—which will include Giovanni Ferrara, a venture partner with Novartis Venture Funds in Cambridge, MA, and Loren Peterson, a managing director of Madison-based Venture Investors, among others—will pick the most promising ideas for the first year’s group. Those entrepreneurs will participate in workshops helping them develop and fine-tune their business plans, Sem says. B2C will eventually whittle the group down to about 10 companies that will pitch to a panel of VCs and biotech experts from Wisconsin and both coasts.

The winning pitch in the product category will receive

Author: Jeff Bauter Engel

Jeff, a former Xconomy editor, joined Xconomy from The Milwaukee Business Journal, where he covered manufacturing and technology and wrote about companies including Johnson Controls, Harley-Davidson and MillerCoors. He previously worked as the business and healthcare reporter for the Marshfield News-Herald in central Wisconsin. He graduated from Marquette University with a bachelor degree in journalism and Spanish. At Marquette he was an award-winning reporter and editor with The Marquette Tribune, the student newspaper. During college he also was a reporter intern for the Muskegon Chronicle and Grand Rapids Press in west Michigan.