PPD Acquires Drug Discovery Startup X-Chem

Contract research organization PPD has acquired biotechnology startup X-Chem, buying the remaining shares of the company that it did not already own a little more than a month before its option to acquire that stake expired.

Waltham, MA-based X-Chem has a drug discovery platform that includes a proprietary library of compounds, as well as drug screening approaches used to identify potential drug candidates. The company says its proprietary DNA-encoded small molecule library has more than 100 billion distinct compounds. PPD did not disclose any financial details for the X-Chem acquisition.

X-Chem makes money from milestone payments and royalties achieved as the compounds picked up by pharmaceutical partners make progress toward becoming commercialized drugs. X-Chem’s technology has attracted a long list of pharma partners including Roche, AstraZeneca, Bayer, and Pfizer.

PPD, based in Wilmington, NC, bought a controlling stake in privately-held X-Chem in 2010. Securities filings for PPD, which was a publicly traded company at the time of the initial investment, show that PPD paid $15.5 million to acquire 60 percent ownership of X-Chem in 2010. PPD had the option to acquire the remaining 40 percent at a company valuation of $70 million, as long as it exercised that option by Oct. 31, 2014, filings show.

X-Chem was formed in 2010 by CEO and founder Richard Wagner. PPD says X-Chem will continue operating as a biotechnology company, retaining its entire staff, including the management team.

 

 

Author: Frank Vinluan

Xconomy Editor Frank Vinluan is a business journalist with experience covering technology and life sciences. Based in Raleigh, he was a staff writer at the Triangle Business Journal covering technology, biotechnology and energy before joining MedCityNews.com as North Carolina bureau chief. Prior to moving to North Carolina’s Research Triangle in 2007 he held business reporting positions at The Des Moines Register and The Seattle Times.