Kyoto Prize Winner Robert Langer on Innovations to Come

Robert Langer, MIT, Kyoto Prize (Photo courtesy Kyoto Prize)

be a very big area. Some of the innovations go across the board. What we just talked about with Viacyte is a great example of tissue engineering, because that involves cell therapies, with better materials; better design of systems that will enable diabetes treatment is certainly one area.
So there are many examples. They range from better cell-therapy kinds of approaches to basic research in learning how to control stem cell growth and differentiation. There are new materials advances, which could include what we just talked about with better materials and better compatibility. There are other properties that you want to do too.

For example, we have a big project with Steve Zeitels [of Massachusetts General Hospital] who is the surgeon for Julie Andrews and other singers. We’re trying to create gels that you could use to replace vocal cords, and that includes a whole range of properties that you want to have. That’s true across the board for any tissue or organ. You want to create just the right materials for that tissue or organ. If you try to make new vocal cords, that’s one set of challenges. New blood vessels is another set of challenges. Heart muscle, that’s another set. It goes on and on.

So what you see in tissue engineering are advances at a basic level, both in terms of understanding the cell therapies, and then in advances in materials to create new kinds of materials, and finally with each tissue or organ there are specific challenges that are critical in enabling you to ultimately make that tissue or organ.

Right now, there is FDA-approved skin, and we see in many cases various clinical trials going on in a lot of areas. For example, there are clinical trials going on to create new corneas, new spinal cords, new cartilage. There are many exciting areas going on with respect to individual therapies, and then there is this broader work that affects all of them.

Kyoto Prize Ceremony 2014 (courtesy Inamori Foundation)
Kyoto Prize Ceremony 2014 (courtesy Inamori Foundation)

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.