In 2010, Xconomy San Diego assembled a panel of biotech visionaries to peer over the horizon and predict what the local life sciences landscape would look like in 2030. But consider how much has changed since 2010 just in the fields of immunotherapy, genomics, and precision medicine. Among San Diego’s big companies, Illumina has literally filled the space once occupied by Biogen—and the buyouts of Life Technologies, CareFusion, Receptos, Seragon, Aragon, and Auspex Pharmaceuticals have reshaped the region’s life sciences landscape. In the wake of these changes, new startups are emerging, new areas of research are heating up, and new controversies have erupted.