ReVision Planning Late-Stage Trial Next Year for Macular Degeneration Drug

San Diego’s ReVision Therapeutics got an encouraging reception over the weekend at a joint meeting in Chicago of the American Academy of Opthalmology and the Middle East-Africa Council of Opthalmology.

Researchers led by Dr. Jason Slakter of the New York University School of Medicine presented results from a mid-stage clinical trial of an experimental drug for treating the “dry” form of age-related macular degeneration (AMD), according to a statement released by the American Academy of Opthalmology. The results show that dry AMD patients at risk of progressing to a more serious form known as “wet” AMD decreased almost two-fold among the patients who took fenretinide, a synthetic derivative of vitamin A.

Slakter also reported that retinal lesion growth was reduced in the fenretinide group. As we reported in August, ReVision has been developing fenretinide as a treatment for dry AMD. The company is planning a late-stage clinical trial to begin in 2011.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.