Vaccine Innovations That Will Expedite Access for the Next Generation of Treatments

As viral pandemics and drug resistant bacteria become more common, it is imperative that the pharmaceutical industry increases its efforts to develop truly revolutionary treatments to combat infectious diseases. One area of focus is the development of new prophylactic and therapeutic vaccines.

When a pandemic strikes, the traditional vaccine development and manufacturing process is cumbersome and time consuming, often leading to gaps in protecting large portions of our population. There is a tremendous need for safer, more effective, shelf-stable, and easy-to-administer (needle-free) vaccines that can easily be stockpiled and rapidly deployed outside the current healthcare system. This is arguably more important in the developing world, where populations are at greater risk of contracting transmissible diseases and generally lack adequate trained healthcare personnel to handle pandemics.

Nanoemulsion-based vaccine adjuvants are an area of research that has great potential to address these needs and lead to breakthrough therapeutic and prophylactic treatments.

The development of unique vaccines with exceptional safety profiles is a very high priority because of the tremendous potential for preventing infections and saving lives, while avoiding the risks that are keeping parents from vaccinating their children. I contracted pertussis (“Whooping cough”) last summer after caring for an unimmunized child, and these cases are becoming more common. In 2011, I hope the medical community will develop innovative new vaccine platforms that address the both the medical and the social problems with vaccination.

[Editor’s Note: This is part of a series of posts from Xconomists and other technology and life sciences leaders from around the U.S. who are weighing in with the top surprises they’ve seen in their respective fields in the past year, or the major things to watch for in 2011.]

Author: James Baker, Jr.

Dr. Baker is the inventor of the platform technology, founder of NanoBio and an internationally recognized expert in immunology and nanotechnology. Dr. Baker invented the NanoStat technology at the University of Michigan, where he is the Ruth Dow Doan Professor of Medicine and Head of Allergy and Immunology at the Medical School. As the Director of the University of Michigan Nanotechnology Institute, Dr. Baker leads a multidisciplinary team of 30 scientists focused on the use of nanotechnology in biomedical applications. He is one of three editors of the National Nanotechnology Initiative’s Research Directives, and a member of the Nanotechnology for Medicine and Biology study section at National Institutes of Health (“NIH”). Dr. Baker is a board-certified internist, allergist and immunologist, a member of American Board of Allergy and Immunology and a Fellow of the American College of Physicians. He is also a Fellow of the American Academy for the Advancement of Science.