San Diego’s Genomatica, a Pioneer in Industrial Biotechnology, Files for IPO

San Diego-based Genomatica, an industrial biotech that uses engineered microorganisms to produce high-value chemicals in fermentation tanks, has submitted plans for an initial public offering, according to a regulatory filing today. The underwriters include Morgan Stanley, J.P. Morgan Securities, and Jefferies & Company, and the company hopes to someday trade under the ticker symbol GENO.

All shares to be sold in the IPO will be offered by Genomatica. The company did not specify the number of shares to be offered, or the price range, but CEO Christophe Schilling indicated in June that Genomatica was looking to raise about $150 million.

The San Diego company, which was founded in 1998, has emerged in recent years as a pioneer in industrial biotechnology. Using a proprietary software technology to model metabolic processes, the company has successfully demonstrated its ability to create a blueprint for genetically engineering microorganisms such as E. coli bacteria to consume renewable resources (sugars) and produce butanediol, or BDO—and more recently—butadiene. Before now, such chemicals were produced by the petrochemical industry, using methane and other fossil fuels as the raw material in CO2-spewing processes.

BDO is used to make a resilient plastic material, which in turn is the raw material for making spandex clothing, running shoes, and dashboards, among other things. In its IPO filing, Genomatica says global demand for BDO in 2009 was 2.8 billion pounds, which equates to a market size of approximately $4 billion (based on prices in June 2011). The company estimates that the global market for butadiene, a basic chemical used in a variety of other everyday products such as tires, carpeting and latex products, is even bigger—about 20 billion pounds and $40 billion. The company says it has identified about 20 other intermediate chemical products for its future product pipeline.

Because of the industrial-scale production required, Genomatica has been forging partnerships with industry partners, such as Tate & Lyle in the United States and Novamont in Europe.

Genomatica was founded in 1998, and operated as a research and development group with specialized expertise in using its proprietary software technology to model metabolic processes. The company funded its operations mostly through collaborative research agreements, grants, and by licensing its software to other researchers. In 2007, the company seemed to re-invent itself—or at least to focus more directly on its current commercialization strategy.

The company says it has raised $84.2 million in total proceeds from the issuance of convertible preferred stock. It’s biggest existing shareholders include Fort Worth, TX-based TPG Biotechnology Partners, which holds 19.1 percent; Menlo Park, CA-based Mohr Davidow Ventures, 17.3 percent; San Bruno, CA-based VantagePoint Venture Partners, 12.6 percent; Palo Alto, CA-based Alloy Ventures, 10.4 percent; and Batios Holdings of the British Virgin Islands, 7.4 percent.

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.