Xconomist of the Week: Larry Smarr’s Quest for ‘Quantified Health’

A couple of months ago, the publisher and CEO of the weekly Strategic News Service Newsletter introduced an article by San Diego Xconomist Larry Smarr, saying, “This issue may be the most important Special Letter we have ever published.”

Smarr’s 23-page article, which takes up the newsletter’s entire Sept. 26 issue, is part scientific paper and part personal odyssey into what Smarr calls his “Quantified Health.” In the 10 years since he moved to San Diego to become founding director of the UC system’s California Institute for Telecommunications and Information Technology (CalIT2), Smarr has scrupulously measured and analyzed his own biological data. In his paper, Smarr writes, “What I have learned about myself both illustrates and foreshadows the ongoing digital transformation of medicine.”

Xconomy Biotech Editor Luke Timmerman previewed this personal experiment last year after Smarr gave a presentation in Seattle. Smarr tells me he initially began by simply charting his weight. “I really wasn’t paying attention to my weight and general health until I came to San Diego from Illinois in 2000,” he says. “Once I looked around at all the fit people here I realized I better pay attention or I might get sent back to the Midwest!”

Through the years, however, Smarr has expanded his survey to include regular blood tests to monitor more than 60 biochemical markers. He now keeps meticulous notes on his diet, exercise, and supplemental vitamins, saying, “I routinely use food and supplements to ‘tune my numbers’ to more optimal levels.” Smarr says he uses the BodyMedia armband and the Fitbit clip to measure his physical activity, caloric burn, and sleep efficiency. He uses the Zeo device to monitor his sleep patterns and the HeartMath‘s emWave Desktop program to measure his stress and train himself to relax.

In 2005, when Smarr detected unusually high levels of a key blood marker for inflammation, his scientific quest escalated to a whole new level of detail—one that included tracking multiple biomarkers in his own stool samples and even obtaining an analysis of his DNA. “Yet this is precisely what the digital revolution in healthcare is all about,” Smarr writes. “The combination of trend-revealing graphs of time series of individual biochemical markers, with population-wide comparisons to people with different health outcomes is transforming biomedical research and ultimately clinical care, into an entirely new paradigm. In this new world, we become personally responsible for

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.