Charting Startups in the Downturn, San Diego’s Biotech Survival Index (Part Deux), Court Dismisses Federal Patent Suit Against Qualcomm, & More SD BizTech News

If there’s a theme to be found in the innovation news for San Diego last week, it might be comings and goings. While some companies are making layoffs or even shuttering their doors, we also found a number of new startups taking root here (although not as many as a year ago).

—In a report on San Diego’s innovation economy, the non-profit business group Connect found 73 new technology companies were started here during the last three months of 2008, a 58 percent decline compared to the year-ago period. It’s a sign the local tech economy is down, but not out.

Luke profiled Amira Pharmaceuticals, a biotech startup founded in 2005 that is developing a drug to treat pulmonary fibrosis. In this recession, it’s worth noting that the three scientists who started Amira joined forces after Merck had shut down the San Diego operation where they had worked.

—A different kind of start-over is San Diego-based SpectraScience (OTCBB: [[ticker:SCIE]]). After salvaging the biomedical equipment maker from bankruptcy in 2004, local entrepreneur Jim Hitchin is just beginning to sell the company’s updated “optical biopsy” machines. The technology combines a low-power, fiber-optic blue laser with computerized spectroscopy.

—Another new biotech that Luke profiled is San Diego’s Pico Pharmaceuticals. The company is using research out of New York’s Albert Einstein College of Medicine to develop highly specific small molecule drugs that bind more tightly to their receptor targets.

—JP (Juha-Pekka) found that Dotmatics, a U.K. bioinformatics and visualization software developer, has opened a satellite office near San Diego as part of its expansion into the U.S. life sciences market.

Sorenson Media, a Salt Lake City-based developer of video compression and encoding software, also has opened a new San Diego office to serve as the central hub of its business operations.

—On the other side of the ledger, I rounded up more layoffs that have come to light in San Diego in recent weeks. They included specialized laser maker Cymer, which with its latest round of 130 cuts has eliminated 38 percent of its workforce since

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.