Regulus Therapeutics Files for IPO as ‘Emerging Growth’ Company

Regulus Therapeutics, MicroRNA

San Diego’s Regulus Therapeutics plans to raise $57.5 million in an IPO that takes advantage of incentives for emerging growth companies provided under the Jump Start Our Business Startups (JOBS) Act passed earlier this year.

In its IPO filing, the preclinical biopharmaceutical says it plans to follow reduced IPO disclosure and financial reporting requirements for five years, or until Regulus no longer qualifies as an emerging growth company. The company says it intend to use proceeds of the offering and a concurrent private placement to advance development of its microRNA drug candidates, capital expenditures, working capital, and other corporate purposes.

The company specializes in RNA interference, or RNAi technology, that uses snippets of ribonucleic acid, or microRNAs to block key signaling pathways linked to many diseases. The lead experimental compounds at Regulus are targeting four areas—cancer, hepatitis C, cardiovascular disease, and fibrotic disorders.

“We believe we have assembled the leading position in the microRNA field, including expertise in microRNA biology and oligonucleotide chemistry, a broad intellectual property estate, key opinion leaders and disciplined drug discovery and development processes,” the company says in its filing.

Regulus was founded in

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.