How To Build a Biotech Cluster That Isn’t Boston or SF

I live and work in Louisville, KY, a city that probably isn’t too different from a lot of communities in the U.S. that are not biotech hubs like San Francisco and Boston. Driven in part by economic development, many in my hometown would like to develop a biotech cluster. But building a biotech cluster is hard and takes time.

We have been hard at work on building a biotech cluster for some time. In 1997, Louisville community leaders produced a report that included developing an economic development niche “biomedical research and healthcare-related services.” The Research Challenge Trust Fund, or Bucks for Brains, started the following year. Bucks for Brains has enabled the University of Louisville to recruit and retain teams of research faculty from some of the best universities in the world. Carl Weissman, the CEO of Seattle-based Accelerator, frequently advises communities to recruit star scientists if they want to create biotech hubs, and Louisville has done it. In August 2011, The Chronicle of Higher Education ran an article on the top 100 universities in biggest gains in federal funding for R&D in sciences and engineering for the period 1999-2009. The University of Louisville ranked fourth on that list with an increase of 263.1 percent over the decade.

Bucks for Brains has helped to increase our intellectual property and technology base. But, those smart scientists are only one piece of the puzzle.Biotech companies need “management talent” who can take a raw idea from a lab and turn it into a finished product. As Xconomy’s Luke Timmerman has said, “management talent is the most important factor in determining whether a company will succeed—even more important than the technology a company starts with.”

This issue of “management talent” is where many aspiring U.S. biotech clusters fall short. For starters, size is an issue. Boston and San Francisco both have populations about equal to the entire state of Kentucky. The Louisville metropolitan statistical area currently ranks 42nd nationally, so we are not exactly small. Nevertheless, we don’t have the sheer volume of people that you’ll find in the bigger hubs.

And, we don’t have a true biotech anchor tenant in our community that “employs a lot of talented people.” There are very few guys and gals walking around the streets of Louisville who have taken a drug to market. The “management talent”—more specifically, people that have made venture capital firms like Domain Associates or Third Rock Ventures money on previous deals—is frequently not here. Fast casual dining? Sure. Energy brokerage? Sure. Healthcare services? Sure. Biologics? No.

We, like a lot of cities, have a biotech people issue. And this is important, because because I subscribe to the “bet on the jockey” cliché.

So what are communities like ours to do? We don’t throw in the towel, but we don’t compete head-on with the Bay Area or Boston, either. First, we realize we are not aspiring to be the next anywhere

Author: Andrew Steen

Andrew Steen has worked with life science start-up companies since 2000, establishing a broad network of contacts with venture capitalists and individuals involved in R&D and business development in pharmaceutical and biotechnology companies throughout the world. At MetaCyte Andy has played a lead role in creating deal flow. He currently serves on the boards of AnosiaVax, Inc., Gnarus Systems, Inc., Pradama Inc., and TrackFive Diagnostics, Inc., Inc., and was a board member of ImmunoTheragnostics Incorporated until its acquisition in December 2008. Andy has been actively engaged in creating the nascent life science industry in Metro Louisville since joining Louisville Medical Center Development Corporation in 2000. MetaCyte Business Lab emerged from Louisville Medical Center Development Corporation in 2002. Prior to joining LMCDC, Andy spent nearly six years with National City Bank of Kentucky where he held a number of positions, culminating as Senior Credit Analyst/Trainer/Credit Officer providing analyses of a wide variety of industries, including healthcare. Andy holds a B.A. from Transylvania University and an M.B.A. from the University of Louisville. He also attended the University of Kentucky College of Law.