Crowdfunding Is Coming to Biotech, so Get Ready for a Wild Ride

Most biotech pros will shrug, or chuckle, if you ask whether crowdfunding will transform life sciences financing in the U.S.

This, after all, is an industry where you often need to raise at least $50 million or $100 million to even have a chance at developing a new drug or medical device. Scraping together a few thousand bucks from individuals on the Internet isn’t going to go very far. One venture capitalist recently told me, “there are a lot of things I worry about, but crowdfunding isn’t one of them.”

Still, I’ve come around to the idea that crowdfunding is going to be disruptive for biotech investment. Starting this year, some cash-strapped startups will find this trend to be godsend. Some small investors will feel fleeced. Insiders who have traditionally had all the power over who gets funded will have to make some tough decisions about whether to pool their money with the masses.

Crowdfunding, for those unfamiliar, is the process in which individuals go on the Internet to donate, loan, or invest in a new company or project. Sites like Kickstarter and Indiegogo have become platforms for making these bets, and for social chit-chat about how they are doing. Often, these campaigns star some entrepreneur who describes his or her new business idea, asks for support, and offers something small in return, like a T-shirt. These are projects that friends and family might have financed before, or maybe angel investors or VCs. Here at Xconomy, we recently ran a small, independent crowdfunding campaign to expand our coverage of innovation to Colorado.

While there have been a few big crowdfunding success stories—one video game developer raised $6.2 million on Kickstarter in November—most of these campaigns run in the thousands or tens of thousands of dollars. There have been some clinical trials financed on crowdfunding, but no biotech I’m aware of has raised big money this way yet.

Health Tech Hatch and Medstartr have gotten some attention for efforts to use crowdfunding for health technologies. But one well-connected startup, a New York-based company called Poliwogg, could end up being the place where little biotech companies raise real money through crowdfunds before they hit the NASDAQ.

Crowdfunding is the kind of thing that 75 million members of the “millennials” generation—those who came of age in the ‘90s and 2000s Internet era—instantly get. Think about it. Just like how anybody can open a TD Ameritrade account and buy shares in Dendreon (NASDAQ: [[ticker:DNDN]]) to express support for prostate cancer R&D and hopefully make money, individuals will soon be able to invest in private and venture-backed startups that were previously off-limits. While most private companies have fewer than 30 investors, the JOBS Act passed by Congress last year enables private companies to stay private even with up to 2,000 investors.

Greg Simon, CEO of Poliwogg

Love the law or loathe it—and the lack of disclosure for pre-IPO companies is something I hate—the only thing holding it back now is some regulatory language from the Securities and Exchange Commission that will clarify the difference between wealthy “accredited” investors and the “non-accredited.” (Essentially, there are more consumer protections being designed for “non-accredited” investors, so they can’t lose their life’s savings on pipe dreams.) Once those regs are published, it will open up a new avenue for investing in thousands of companies, including your local cancer drug developers. And this opening of the floodgates is happening precisely at a moment when biotech is in dire need of cash, as the venture capital industry is going through a historic contraction.

“The potential global size off this kind of funding of equity—and I’m not talking about Kickstarter, Indiegogo, or the nonprofit stuff—is $1 trillion or more,” says Greg Simon, CEO of Poliwogg. “If we were sitting here in 1981, and you asked me ‘how big do you think it will be when the Baby Boomer generation hits the stock market,’ and I had said that the stock market will go from 1,000 to 10,000, you’d probably say I was crazy. This is going to be as big, if not bigger.”

Before you dismiss this as breathless hype, the Poliwogg crew brings a lot of experience to this task. Jeff Feldman previously worked on exchange-traded funds (ETFs) at XShares Advisors, which he sold to Deutsche Bank in 2010. Simon was a top domestic policy aide to former vice president Al Gore, the CEO of the Michael Milken-backed nonprofit FasterCures, and a senior vice president at Pfizer. Samuel Wertheimer was a partner at OrbiMed Advisors, a big Wall Street investor in healthcare. Les Funtleyder has been an analyst and source for healthcare journalists for years. The board includes Tommy G. Thompson, the former U.S. Secretary of Health and Human Services. These people know the issues in healthcare, and who’s who.

Poliwogg, well aware of how the JOBS Act opens the door to crowdfunding for biomedical R&D, has spent the last year building a social platform for these kind of transactions. It’s focusing in healthcare, community-based small businesses, and what it calls “high-yield assets” like commercial leases for blue-chip tenants like FedEx, Simon says. Each of these categories has a different risk/reward profile. People who gravitate to biotech are “passion capital” investors, Simon says, who have deep desire to do something good for, say, prostate cancer.

Here’s how it is supposed to work. Poliwogg, under the law, will advertise that it’s a new place for people to invest in healthcare. In the beginning, it will allow anybody to look

Author: Luke Timmerman

Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.