Domain Elite Invests $6.5M in GI Device Maker to Expand in China

Beijing, China, Skyline, City

When Domain Associates unveiled an initiative to commercialize new healthcare technologies in China last year, partner Brian Halak said one of the big challenges would be getting biomedical innovators to license their technologies for the huge, but still-developing market.

The venture firm, which is based in San Diego and Princeton, NJ, has been thinking outside the box for the past few years in terms of developing new business models for venture investing in the life sciences. Halak told me last year that the concept of Domain’s initiative in China was comparable in some ways to The Foundry, the Menlo Park, CA-based incubator for medical devices.

Now, after 13 months, the partnership that Domain established with Elite Consulting in Beijing is announcing its first move—although it’s not a licensing deal per se. Instead, the Domain Elite partnership says it has invested $6.5 in Smart Medical Systems, an Israeli company with innovative endoscopy and colonoscopy products, as part of a multi-phase effort to move Smart Medical’s gastrointestinal technologies into China, Hong Kong, and Taiwan.

Domain Elite has some other deals in the works as well, and Halak says each one has been structured a little differently. In the Smart Medical deal, Halak said a tight collaboration with the device maker proved to be a better approach than trying to in-license the Israeli company’s technology.

Smart Medical's endoscope
Smart Medical’s endoscope

Smart Medical has a subsidiary in Hong Kong, and apparently already had ambitions in the region. Still, it can be difficult for a small company to pursue the healthcare market in China. So part of Domain Elite’s $6.5 million investment is allocated directly to the subsidiary, according to a joint statement being released today.

Smart Medical, founded in 2005 in Ra’anana, Israel, has developed an approach that incorporates balloon catheters in the design of its endoscopes and colonoscopes, the medical devices that use a flexible tube equipped with a camera to look at the inside the human digestive tract. An endoscopy procedure examines the upper gastrointestinal (GI) tract (the esophagus, stomach, and small intestines) while a colonoscopy looks at the lower portion of the GI (large intestine, colon, and rectum).

Smart Medical Systems NaviAid G-EYE endoscope 2In the United States, such examinations are used mostly to screen for signs of cancer along the inner wall of the GI tract. The device used in the exam also has a tool that can be used to remove pre-cancerous polyps in the gut.

Smart Medical’s flagship product is designed with a balloon that can be inflated to make it easier for doctors to find pre-cancerous polyps, which can be obscured by the natural folds of the colon. The company also has designed another balloon device that attaches to the end of its endoscope, so doctors using the device can advance the endoscope faster and farther into the gut.

Procedures that usually require

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.