[Correction: 1/11/10, 9:15 am Pacific, with distinction between IL-6 and IL-6 receptor.] Genentech, the U.S.-based unit of Swiss pharmaceutical giant Roche, said the FDA has granted clearance to start selling a new drug for rheumatoid arthritis. The treatment, tocilizumab (Actemra), is the first approved antibody engineered to block the receptor for an inflammatory protein called IL-6, that is overactive in patients with rheumatoid arthritis. Bothell, WA-based Alder Biopharmaceuticals is attempting to block the IL-6 protein with a “fast-follower” antibody called ALD518, which is being co-developed with Bristol-Myers Squibb.
Author: Luke Timmerman
Luke is an award-winning journalist specializing in life sciences. He has served as national biotechnology editor for Xconomy and national biotechnology reporter for Bloomberg News. Luke got started covering life sciences at The Seattle Times, where he was the lead reporter on an investigation of doctors who leaked confidential information about clinical trials to investors. The story won the Scripps Howard National Journalism Award and several other national prizes. Luke holds a bachelor’s degree in journalism from the University of Wisconsin-Madison, and during the 2005-2006 academic year, he was a Knight Science Journalism Fellow at MIT.
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