A year ago, the leading Chinese Internet company Tencent Holdings pegged the global number of artificial intelligence researchers and professionals at 300,000 or less—just as the unmet demand for such experts was pushing salary offers to as much as $1 million. In February, the Canadian firm Element AI estimated that talent pool at no more than … Continue reading “Diffbot’s A.I. Engine Draws Global Map of Machine Learning Expertise”
Category: San Francisco
OncoMed’s Saga Ends in Reverse Merger with UK-Based Mereo BioPharma
OncoMed Pharmaceuticals attracted hundreds of millions of dollars from investors and pharmaceutical partners with compounds it developed to target cells that drive cancer growth. But after a series of clinical trial stumbles and the dissolution of its drug development alliances over the last two years, OncoMed is now serving as a vehicle for a UK-based … Continue reading “OncoMed’s Saga Ends in Reverse Merger with UK-Based Mereo BioPharma”
Alto Lands $50M as Pharmacy Sector Embraces E-Commerce Lessons
[Updated 12/5/18, 5:16 pm. See below.] The pharmacy industry’s transformation is accelerating, as traditional drug retailers strike deals to expand their businesses and fend off technology startups encroaching on their territory. The latest salvo in the increasingly competitive sector is a $50 million investment in Alto Pharmacy, a San Francisco-based “digital pharmacy” startup that has … Continue reading “Alto Lands $50M as Pharmacy Sector Embraces E-Commerce Lessons”
Adherium Aims to Improve Asthma Patient Outcomes with Smart Inhalers
Asthma is the third-ranking cause of hospitalization for children under 15 years of age in the U.S., and it’s the leading cause of missed school among children ages 5 to 17. Missed school can lead to missed work and lost income if parents need to stay home to care for their sick kids, potentially leading … Continue reading “Adherium Aims to Improve Asthma Patient Outcomes with Smart Inhalers”
“JK Told Me He Was Planning This”: A CRISPR Baby Q&A with Matt Porteus
Last week, Chinese researcher He Jiankui stunned the world with his claim to have created the world’s first gene-edited humans. He said he had used CRISPR-Cas9 to change the DNA of the embryos of twin girls, to make them immune to HIV infection, then implanted them in their mother’s womb. He announced on video the … Continue reading ““JK Told Me He Was Planning This”: A CRISPR Baby Q&A with Matt Porteus”
BCMA Day: At ASH ‘18, Cell Therapies For Myeloma Take Center Stage
The treatment landscape for multiple myeloma, a deadly cancer of the bone marrow that affects about 30,000 Americans every year, has changed significantly over the past decade. And more changes look to be on the way. Take the results of a Phase 3 study just reported today at the American Society of Hematology’s (ASH) yearly … Continue reading “BCMA Day: At ASH ‘18, Cell Therapies For Myeloma Take Center Stage”
Growing Fast? GotSpot Aims to Pair Young Firms With Short-Term Digs
Houston—It’s not just biotech companies that must cross the valley of death on their way to commercial success. Everyday Mom-and-Pop shops, too, have to navigate the tricky adolescence period when their businesses are starting to take off but they don’t have the capital to rent out the space and equipment to fulfill larger orders—a problem … Continue reading “Growing Fast? GotSpot Aims to Pair Young Firms With Short-Term Digs”
Event-Stream Hack Is Not Cause For Panic About Open-Source Security
News last week that event-stream, the popular open-source code library managed by NPM, had been compromised by a hacker (or hackers) looking to steal Bitcoin led some to question the underlying security of the open-source components that they are using in their software. According to reports, a hacker gained control of the event-stream package by … Continue reading “Event-Stream Hack Is Not Cause For Panic About Open-Source Security”
15Five Lands $8M to Provide Coaching Software to More Managers
[Updated 12/4/18 9:20 am. See below.] San Francisco-based performance management startup 15Five, whose mission is to torpedo annual performance reviews for workers and replace them with supportive weekly coaching by managers, announced today it raised $8 million in a Series A funding round. 15Five gets its name from the feedback and coaching process that its … Continue reading “15Five Lands $8M to Provide Coaching Software to More Managers”
Superpedestrian Rolls Out Smarter, Hardier E-Scooter for Sharing
It’s the diagnosis of Superpedestrian CEO Assaf Biderman that bike- and scooter-share startups know far too little about bikes and scooters. His Cambridge, MA-based transportation technology startup is announcing its foray into scooter sharing today with what it says is a smart, durable, and efficient scooter of its own. Biderman sees the feverish industry—crowded with … Continue reading “Superpedestrian Rolls Out Smarter, Hardier E-Scooter for Sharing”
Brain Corp. Agrees to Power More Walmart Self-Driving Floor Scrubbers
Early next year the floors of hundreds of Walmart stores will be cleaned by self-driving scrubbing machines powered by software developed by San Diego’s Brain Corp. On Monday, Brain said Walmart (NYSE: [[ticker:WMT]]), the world’s largest retailer, will be using BrainOS, its proprietary operating system, in 360 such autonomous machines by Jan. 31, the end … Continue reading “Brain Corp. Agrees to Power More Walmart Self-Driving Floor Scrubbers”
ASH 2018: Three Up, Two Down as Big Blood Disease Meeting Rolls On
[Updated 4:37 p.m. See below.] Last week, Xconomy previewed the American Society of Hematology’s big meeting in San Diego, the largest medical gathering in the country on blood diseases. We took a deep dive into five specific disease areas under scrutiny, from lymphoma to hemophilia to sickle cell disease and more. News related to those … Continue reading “ASH 2018: Three Up, Two Down as Big Blood Disease Meeting Rolls On”
ResMed Boosts Connected Health Play With $225M Propeller Health Deal
[Updated 12/3/18, 3:30 pm, with CEO comments.] ResMed has inked a $225 million deal to acquire Propeller Health, in the latest endorsement of Internet-connected devices for healthcare. The acquisition, which is expected to close by the end of March 2019, continues San Diego-based ResMed’s (NYSE: [[ticker:RMD]]) “connected healthcare” push that began about five years ago, … Continue reading “ResMed Boosts Connected Health Play With $225M Propeller Health Deal”
WI Syndication Group Seeks More Investor Team-ups to Spur Big Exits
Many startup investments involve multiple investors these days, but it’s not always easy to assemble a group of backers necessary to close the deal. Wisconsin—which has a small local pool of venture capital and aspirations to churn out more high-growth startups—is one of the places experimenting with tactics to nurture relationships and collaboration between investors … Continue reading “WI Syndication Group Seeks More Investor Team-ups to Spur Big Exits”
Volvo Expands In Silicon Valley As Auto Innovation Goes West
As GM announced a wave of auto plant closures in the North American heartland this week at the cost of thousands of jobs, Sweden’s Volvo Cars was expanding its U.S. presence, both in Silicon Valley and at a new South Carolina factory. Like Detroit-based GM (NYSE: [[ticker:GM]]), which is shifting its attention from traditional auto manufacturing … Continue reading “Volvo Expands In Silicon Valley As Auto Innovation Goes West”
Occipital Reaches Turning Point with New 3D Sensor for Drones, VR
Occipital, the San Francisco-based spatial computing startup, first planted its flag in computer vision tech five years ago when it released a plug-in sensor, billed as the first 3D sensor created for mobile devices such as the iPad. Called Structure Sensor, it allows users—mostly software developers and gamers—to capture 3D models or images in order … Continue reading “Occipital Reaches Turning Point with New 3D Sensor for Drones, VR”
Bio Roundup: CRISPR Babies, Blood Diseases, Big Cancer Nod & More
This was one of those weeks when the world seemed to slip into a new era with no going back. A Chinese researcher, He Jiankui, claimed he helped bring to life two genetically engineered babies, twin girls with a gene disabled to make them immune to HIV infection. Even though the technology He used—in vitro … Continue reading “Bio Roundup: CRISPR Babies, Blood Diseases, Big Cancer Nod & More”
Women Inspire NYC’s Tech Startups to Dream Bigger
As a native New Yorker, it may not come as much of a surprise that growing up I wanted to work in finance. In fact, I put myself through NYU Stern while working for companies like IBM, Prudential, and Merrill Lynch, and joined Goldman Sachs upon graduation. You could say I had made it in … Continue reading “Women Inspire NYC’s Tech Startups to Dream Bigger”
Coinbase Backs Flipside Crypto Amid “Healthy” Currency Selloff
(Updated 11/29/18, 11 a.m. with additional funding details) The crash in digital currency values has tossed fuel on the already raging fire of skepticism around many crypto projects, which are suspected as scams masquerading as a technology of tomorrow. But the price retreat—and the accompanying losses to crypto speculators—are welcome news to Dave Balter, CEO … Continue reading “Coinbase Backs Flipside Crypto Amid “Healthy” Currency Selloff”
ViaCyte Raises $80M to Prep for the Clinic Now, Perhaps an IPO Later
ViaCyte is recruiting patients for clinical trials testing its experimental stem cell-based diabetes treatment. Now it has $80 million to support that work, and also prepare for something more: a possible IPO. The financing, a Series D round of investment, includes so-called crossover investors that back both public and private companies. CEO Paul Laikind told … Continue reading “ViaCyte Raises $80M to Prep for the Clinic Now, Perhaps an IPO Later”
Auris Health Lands $220M to Expand Sales of Lung Testing Medical Robot
Auris Health has already received regulatory clearance to sell its medical robot in the U.S. Now it has $220 million in funding to help it place the technology in the hands of surgeons. The latest investment, which the company calls “growth financing,” was led by Partner Fund Management. Redwood City, CA-based Auris says it will … Continue reading “Auris Health Lands $220M to Expand Sales of Lung Testing Medical Robot”
Workers, Investors, Trump React to Cuts as GM Clears Way for Mobility
On Monday, GM made an announcement that rattled Wall Street, automotive analysts, its own workforce, and President Trump . A day after the car manufacturer announced plans to close factories in Michigan, Ohio, Maryland, and Oshawa, Ontario, Trump threatened on Twitter Tuesday afternoon to take away GM’s federal electric car subsidies, which it uses to … Continue reading “Workers, Investors, Trump React to Cuts as GM Clears Way for Mobility”
Last Chance to Save on Tickets for Xconomy’s Bay Area Biotech Event
There’s just one week left until Xconomy’s latest biotech event, “San Francisco Biotech: The Next Generation.” Don’t let the clock run out while you can still save some cash on a ticket. Next Wednesday, Dec. 5, company founders and visionary scientists will share how they are pursuing new ideas and breaking biotech boundaries. Don’t wait … Continue reading “Last Chance to Save on Tickets for Xconomy’s Bay Area Biotech Event”
Under Fire, He Jiankui Says He’s “Proud” to Help Make CRISPR’d Babies
[Updated, 11/28/18, 12:20pm ET. See below.] Is there another CRISPR baby on the way? In his first public appearance since his stunning claim, released on YouTube Sunday, that he helped bring the first genome-edited humans into the world, He Jiankui, a genomics researcher at Southern University of Science and Technology of China in Shenzhen, said … Continue reading “Under Fire, He Jiankui Says He’s “Proud” to Help Make CRISPR’d Babies”
Roche Gains Place in NASH Race with Purchase of Jecure Therapeutics
Roche is acquiring San Diego startup Jecure Therapeutics, with hopes of turning Jecure’s early research into a drug or drugs that treat the liver disease NASH. Through its South San Francisco, CA-based Genentech division, the Swiss pharmaceutical giant will acquire Jecure, whose work has yet to reach clinical studies, the companies announced Tuesday. No financial … Continue reading “Roche Gains Place in NASH Race with Purchase of Jecure Therapeutics”
Genetic Medicine: FDA OKs 2nd Cancer Drug That Targets DNA, Not Tissues
[Updated 11/26/18. See below.] Going deeper into the new world of genetic medicine, the FDA has for the second time approved a drug that targets a tumor’s DNA fingerprint, no matter where in the body that cancer is found. And more could be on the way. The drug is larotrectinib (Vitrakvi), from Loxo Oncology (NASDAQ: … Continue reading “Genetic Medicine: FDA OKs 2nd Cancer Drug That Targets DNA, Not Tissues”
As It Aims to Go Public, Seismic Taps Former ServiceNow Exec as CFO
Seismic, one of San Diego’s most prominent enterprise software companies, has tapped a member of the team behind one of the region’s most successful tech startup stories to prep for its own prospective market debut. The software developed by Seismic, part of the relatively new sales enablement industry, helps marketing and sales teams manage, automate … Continue reading “As It Aims to Go Public, Seismic Taps Former ServiceNow Exec as CFO”
Necessity Vs. Innovation-Based Entrepreneurs
What makes someone an entrepreneur? Most simply defined, an entrepreneur is a person who identifies a need and starts a business to fill that void. But others will argue that a “true” entrepreneur must come up with an innovative new product or service and then operates their business to sell and profit from that innovation. … Continue reading “Necessity Vs. Innovation-Based Entrepreneurs”
ASH 2018: A Guide to the Latest for Blood-Borne Cancers and More
[Note: Ben Fidler co-authored this report.] This weekend, San Diego will host the annual American Society of Hematology conference, the largest U.S. medical gathering to get the latest on blood diseases, and a venue for updates on some of the most cutting-edge biotechnologies that only a few years ago seemed like science fiction. Using the … Continue reading “ASH 2018: A Guide to the Latest for Blood-Borne Cancers and More”
Diversity in Venture Capital: Scenes From Culture Shifting Weekend
While women and minorities make up 70 percent of the population, less than two percent of the tens of trillions of dollars in the asset management industry are entrusted to women or minorities. In recent years, gains have been made among women in venture capital. Diversity beyond gender, though, continues to lag. That’s part of … Continue reading “Diversity in Venture Capital: Scenes From Culture Shifting Weekend”
Immigrants Are Key to Winning the AI Arms Race
If we want to create jobs and economic opportunity here in the U.S., we’re going to need immigrants. Not only have they pioneered our country’s greatest achievements, bringing you everything from hot dogs to YouTube, but today they serve at the cutting edge of our foremost industries. Nowhere is this more true than in the … Continue reading “Immigrants Are Key to Winning the AI Arms Race”
Cybersecurity Startup AttackIQ Hires New, Bay Area-Based CEO
Cybersecurity startup AttackIQ has appointed veteran tech executive Brett Galloway as its new CEO. AttackIQ said Galloway is taking over the role from Carl Wright, who has been named chief commercial officer. Wright was hired as chief revenue officer in August 2017. The company said he was named interim CEO in September of this year. … Continue reading “Cybersecurity Startup AttackIQ Hires New, Bay Area-Based CEO”
PellePharm Inks $70M Deal with LEO Pharma for Skin Cancer Drug
PellePharm now has a partner to finance late-stage clinical tests of its experimental treatment for a rare skin cancer that has no FDA-approved drug treatment. Denmark-based LEO Pharma has agreed to pay $70 million to PellePharm for the biotech startup’s Phase 3 study of patidegib, a topical gel developed to prevent and treat Gorlin syndrome. … Continue reading “PellePharm Inks $70M Deal with LEO Pharma for Skin Cancer Drug”
How Blockchain Is Finding a Place at Your Thanksgiving Table
The food we buy in grocery stores and restaurants has a story to tell about where it came from and each step it took on its journey to your dinner table. Blockchain technology can help tell that tale. The story many food companies want to tell these days is about safety. Earlier this year, an … Continue reading “How Blockchain Is Finding a Place at Your Thanksgiving Table”
Uber Expands Its E-Bike Service, Jump, to 2 More West Coast Cities
Hundreds of red, “dockless” electronic bikes appeared on the streets of San Diego and Seattle on Monday, the latest cities in which Uber introduced its e-bike program, Jump. The expansion comes days after Uber began rolling out the bike-sharing service across Los Angeles. The San Francisco-based ride-hailing giant acquired Jump Bikes, a Brooklyn e-bike sharing … Continue reading “Uber Expands Its E-Bike Service, Jump, to 2 More West Coast Cities”
Plant-Based Burger Maker Beyond Meat Cooks Up Plans for an IPO
We’ll soon find out if Wall Street has the appetite for investing in alternative meat technology. Beyond Meat, a maker of plant-based meat products, has filed for an IPO. The El Segundo, CA-based company set a preliminary target of $100 million for the stock offering, a figure that will likely change as the company moves … Continue reading “Plant-Based Burger Maker Beyond Meat Cooks Up Plans for an IPO”
X·CON 2018: Photos From Three Innovation Days in November
On November 4-6, Xconomy organized a meeting of the minds—an elite gathering of leaders in technology, business, healthcare, education, and energy—to discuss and demonstrate the key trends in their fields, heading into next year. Our expert speakers and attendees at X·CON 2018 tackled everything from the impact of artificial intelligence on enterprises to the emerging … Continue reading “X·CON 2018: Photos From Three Innovation Days in November”
Human Space Travel as a Platform to Accelerate Biomedical Innovation
A manned mission to Mars is slated for as early as 2024, but there are serious health risks that must be mitigated in order for such a mission to be successful. The most pressing risk identified by NASA is radiation exposure. Instead of stunting our spirit of exploration, there is an urgent need to develop effective radioprotection strategies to … Continue reading “Human Space Travel as a Platform to Accelerate Biomedical Innovation”
Wonolo Scores $32M to Expand Blue-Collar Gig Workers’ Marketplace
Wonolo, which runs a marketplace where companies can find fill-in staffers for jobs like stocking store shelves and warehouse chores, announced Monday that it raised $32 million in a Series C funding round led by Bain Capital Ventures. Bain Capital also invested this year in another tech startup focused on blue collar workers: UpKeep, which … Continue reading “Wonolo Scores $32M to Expand Blue-Collar Gig Workers’ Marketplace”
Bio Roundup: Moderna’s IPO, Arena’s Comeback, E-Cig Survey & More
Thanksgiving is around the corner and this week delivered a bounty of deals that have a number of life science companies expressing their thanks a little early. One deal saw a company land a whopping $800 million upfront for a rights to a drug still in clinical testing. Another biotech landed a $98 million investment … Continue reading “Bio Roundup: Moderna’s IPO, Arena’s Comeback, E-Cig Survey & More”
Silicon Valley Advisory: Make Talent Retention Personal
It took me by complete surprise. Here I was thinking we were on the same page, that we were doing some good things together and, despite some challenges, we made a pretty good team. So, when one of my brightest early talent employees walked into my office to tell me he was leaving, I asked … Continue reading “Silicon Valley Advisory: Make Talent Retention Personal”
Airspace Technologies Brings In $20M to Scale Its Logistics Business
[Updated 5:20 p.m. See below.] Having to wait for a package to arrive generally doesn’t result in severe consequences, besides perhaps a feeling of frustration. Some deliveries, however, are only useful if they arrive on time. Logistics startup Airspace Technologies says its software, developed specifically for time-sensitive shipments—donated organs slated for transplant and replacement parts … Continue reading “Airspace Technologies Brings In $20M to Scale Its Logistics Business”
Genentech’s Elizabeth Jeffords Joins Alkahest C-Suite
Elizabeth Jeffords has joined Alkahest as chief commercial and strategy officer. Jeffords comes to the San Carlos, CA, biotech from Roche subsidiary Genentech, where she was vice president of the unit’s U.S. ophthalmology portfolio. Alkahest develops therapies for age-related diseases. The company’s pipeline includes drug candidates for Alzheimer’s disease and age-related macular degeneration.
Nebula Genomics Touts Free DNA Sequencing to Coax Health Data Sharing
A growing number of startups are trying to encourage people to share genomic and other health data for research purposes by offering them some form of compensation. Now, as competition in this young sector ramps up, one of the big questions is what type of incentive will attract the most individuals. The latest experiment comes … Continue reading “Nebula Genomics Touts Free DNA Sequencing to Coax Health Data Sharing”
Data Starts Stretch Run for UniQure’s Upgraded Hemophilia Gene Therapy
The race to treat hemophilia with gene therapy, a one-time, long-lasting infusion, is entering its final stages. And with new data released this morning, Dutch and Lexington, MA, firm UniQure has finalized its plans to be among the top finishers. UniQure (NASDAQ: [[ticker:QURE]]) today disclosed preliminary results from a tiny mid-stage study of a gene … Continue reading “Data Starts Stretch Run for UniQure’s Upgraded Hemophilia Gene Therapy”
Synthorx Files for IPO to Advance Enhanced Cytokine Drugs
Synthetic biology company Synthorx is laying plans for an initial public offering to raise money to advance its suite of enhanced cytokine drugs. The San Diego-based company says it wants to use the proceeds to put its lead product candidate, an investigational cancer therapy that’s based on the drug interleukin-2 (IL-2), through dose escalation and … Continue reading “Synthorx Files for IPO to Advance Enhanced Cytokine Drugs”
Bain Capital Ventures Nets $1B Funding to Fuel New Round of Tech Bets
Bain Capital Ventures has raised $1 billion to pour into technology companies large and small across a swath of industries, the largest single round of fundraising in the firm’s history. The cash includes a $650 million core fund—that’ll be aimed half at early stage startups and half at later-stage growth companies—as well as a $250 … Continue reading “Bain Capital Ventures Nets $1B Funding to Fuel New Round of Tech Bets”
Amazon Ends “HQ” Search, Pledges to Spend $5B on New Sites in NY, VA
The wait is finally over. Amazon said Tuesday it plans to significantly expand its presence in the New York City and Washington, DC, metropolitan areas beginning next year. The announcement was widely expected following news reports identifying the locales as likely winners of Amazon’s lengthy search process for an additional “headquarters,” as the company is … Continue reading “Amazon Ends “HQ” Search, Pledges to Spend $5B on New Sites in NY, VA”
GreatCall Expands Lyft Partnership to Pick Up Seniors Nationwide
GreatCall, the maker of the Jitterbug cellphone and other products and services for older adults, has extended its partnership with the San Francisco-based ride-hailing company Lyft to offer GreatCall customers the ability to schedule rides without a smartphone app. No financial terms were disclosed. The San Diego-based healthtech company said Tuesday it is rolling out … Continue reading “GreatCall Expands Lyft Partnership to Pick Up Seniors Nationwide”
CEOs and Scientific Founders: Tips for a Long and Successful Marriage
It seemed like the perfect match: A scientist founder from a top-tier academic institution; A technological innovation based on years and millions of dollars of federally-funded research in a university lab; And a successful entrepreneur and industry veteran named as the CEO of the startup that would take the work forward. But soon after the … Continue reading “CEOs and Scientific Founders: Tips for a Long and Successful Marriage”